Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel. (Q51766345)

11 April 2018

title

Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel. (English)

1 reference

11 April 2018

3

Paul Linsdell

1 reference

11 April 2018

Ryan G Holstead

1

1 reference

11 April 2018

Man-Song Li

series ordinal

2

1 reference

11 April 2018

publication date

28 July 2011

1 reference

11 April 2018

number of pages

9

1 reference

Journal of Membrane Biology

inferred from page(s)

published in

1 reference

11 April 2018

volume

243

1 reference

11 April 2018

issue

1-3

1 reference

11 April 2018

page(s)

15-23

1 reference

11 April 2018

https://scigraph.springernature.com/pub.10.1007/s00232-011-9388-0

exact match

0 references

cites work

Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

The role of cystic fibrosis transmembrane conductance regulator phenylalanine 508 side chain in ion channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

The ABC protein turned chloride channel whose failure causes cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Coupled movement of permeant and blocking ions in the CFTR chloride channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Maximization of the rate of chloride conduction in the CFTR channel pore by ion-ion interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Point mutations in the pore region directly or indirectly affect glibenclamide block of the CFTR chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Multiple membrane-cytoplasmic domain contacts in the cystic fibrosis transmembrane conductance regulator (CFTR) mediate regulation of channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Relationship between anion binding and anion permeability revealed by mutagenesis within the cystic fibrosis transmembrane conductance regulator chloride channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Location of a common inhibitor binding site in the cytoplasmic vestibule of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Disulphonic stilbene block of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a mammalian cell line and its regulation by a critical pore residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Adenosine triphosphate-dependent asymmetry of anion permeation in the cystic fibrosis transmembrane conductance regulator chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Non-pore lining amino acid side chains influence anion selectivity of the human CFTR Cl- channel expressed in mammalian cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Molecular determinants of anion selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Using a cysteine-less mutant to provide insight into the structure and mechanism of CFTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Cystic fibrosis transmembrane conductance regulator (CFTR) anion binding as a probe of the pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Novel pore-lining residues in CFTR that govern permeation and open-channel block

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

The interpretation of protein structures: Total volume, group volume distributions and packing density

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

CFTR: Ligand exchange between a permeant anion ([Au(CN)2]-) and an engineered cysteine (T338C) blocks the pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Halide permeation in wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Correctors promote maturation of cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by binding to the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Ionic Blockage of Sodium Channels in Nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Intracellular loop between transmembrane segments IV and V of cystic fibrosis transmembrane conductance regulator is involved in regulation of chloride channel conductance state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Direct comparison of NPPB and DPC as probes of CFTR expressed in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Architecture of the cystic fibrosis transmembrane conductance regulator protein and structural changes associated with phosphorylation and nucleotide binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Evidence that extracellular anions interact with a site outside the CFTR chloride channel pore to modify channel properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00232-011-9388-0

Molecular determinants of Au(CN)(2)(-) binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl(-) channel pore

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21796426

12 December 2020

inferred from PubMed ID database lookup

Identification of a region of strong discrimination in the pore of CFTR.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21796426

12 December 2020

inferred from PubMed ID database lookup

Multiple inhibitory effects of Au(CN)(2-) ions on cystic fibrosis transmembrane conductance regulator Cl(-) channel currents

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21796426

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00232-011-9388-0

1 reference

11 April 2018

PubMed ID

21796426

1 reference

11 April 2018