N-(furan-2-ylmethyl)-N-methylprop-2-yn-1-amine (F2MPA): A potential cognitive enhancer with MAO inhibitor properties. (Q51733605)

http://europepmc.org/abstract/MED/24848125

11 April 2018

title

N-(furan-2-ylmethyl)-N-methylprop-2-yn-1-amine (F2MPA): A potential cognitive enhancer with MAO inhibitor properties. (English)

1 reference

http://europepmc.org/abstract/MED/24848125

11 April 2018

1 reference

1

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14 May 2020

Philippe De Deurwaerdère

10

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14 May 2020

Roberto Colangeli

3

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14 May 2020

author name string

Isela García

2

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14 May 2020

Massimo Pierucci

4

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14 May 2020

Marcos L Rivadulla

5

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14 May 2020

Elena Soriano

6

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14 May 2020

Mourad Chioua

7

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14 May 2020

Laura Della Corte

8

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14 May 2020

Matilde Yáñez

9

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14 May 2020

Yagamare Fall

11

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14 May 2020

José Marco-Contelles

12

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14 May 2020

publication date

21 May 2014

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http://europepmc.org/abstract/MED/24848125

11 April 2018

published in

CNS Neuroscience & Therapeutics

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14 May 2020

volume

20

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14 May 2020

issue

7

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14 May 2020

page(s)

633-640

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Monoamines tissue content analysis reveals restricted and site-specific correlations in brain regions involved in cognition

14 May 2020

cites work

1 reference

Biogenic amines and their metabolites in Alzheimer's disease: noradrenaline, 5-hydroxytryptamine and 5-hydroxyindole-3-acetic acid depleted in hippocampus but not in substantia innominata.

21 January 2018

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Ascending monoaminergic systems alterations in Alzheimer's disease. translating basic science into clinical care

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Monoamine oxidase-B inhibition in Alzheimer's disease

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Levodopa ameliorates learning and memory deficits in a murine model of Alzheimer's disease.

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Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease.

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Propargylamine-derived multitarget-directed ligands: fighting Alzheimer's disease with monoamine oxidase inhibitors

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Inhibitor design for monoamine oxidases

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Selective inhibition of monoamine oxidase A or B reduces striatal oxidative stress in rats with partial depletion of the nigro-striatal dopaminergic pathway.

21 January 2018

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Relevance of benzyloxy group in 2-indolyl methylamines in the selective MAO-B inhibition

21 January 2018

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Elements of a neurobiological theory of hippocampal function: the role of synaptic plasticity, synaptic tagging and schemas

21 January 2018

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A synaptic model of memory: long-term potentiation in the hippocampus

21 January 2018

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Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity.

21 January 2018

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Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility.

21 January 2018

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Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator

21 January 2018

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Rhodium(I)-catalyzed allenic carbocyclization reaction affording delta- and epsilon-lactams

21 January 2018

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Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

21 January 2018

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Long-lasting potentiation of the dentate gyrus population spike by norepinephrine.

21 January 2018

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The antidepressant phenelzine enhances memory in the double Y-maze and increases GABA levels in the hippocampus and frontal cortex of rats.

21 January 2018

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Selegiline reduces N-methyl-D-aspartic acid induced perturbation of neurotransmission but it leaves NMDA receptor dependent long-term potentiation intact in the hippocampus

21 January 2018

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Effects of the monoamine oxidase A inhibitor moclobemide on hippocampal plasticity in GR-impaired transgenic mice

21 January 2018

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Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate].

21 January 2018

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Bifunctional drug derivatives of MAO-B inhibitor rasagiline and iron chelator VK-28 as a more effective approach to treatment of brain ageing and ageing neurodegenerative diseases

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Chronic L-deprenyl or L-amphetamine: equal cognitive enhancement, unequal MAO inhibition.

21 January 2018

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Lack of protection of monoamine oxidase B-deficient mice from age-related spatial learning deficits in the Morris water maze

21 January 2018

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Alzheimer's disease and epilepsy: insight from animal models

21 January 2018

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High dose of 8-OH-DPAT decreases maximal dentate gyrus activation and facilitates granular cell plasticity in vivo

21 January 2018

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Inhibition of MAO-A activity enhances behavioural activity of rats assessed using water maze and open arena tasks

21 January 2018

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12 December 2020

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

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12 December 2020

Norepinephrine and the dentate gyrus

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12 December 2020

Effects of serotonin releasers on dentate granule cell excitability in the rat

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12 December 2020

Impaired LTP- but not LTD-like cortical plasticity in Alzheimer's disease patients.

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12 December 2020

Increased population spike amplitude in the dentate gyrus following systemic administration of 5-hydroxytryptophan or 8-hydroxy-2-(di-n-propylamino)tetralin

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12 December 2020

L-deprenyl (selegiline) decreases excitatory synaptic transmission in the rat hippocampus via a dopaminergic mechanism.

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12 December 2020

Identifiers

DOI

10.1111/CNS.12284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493173&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493173&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493173&resulttype=core&format=json