Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1. (Q51732026)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Clemens Feistritzer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

José A Fernández

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

John H Griffin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Matthias Riewald

5

1 reference

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25 January 2020

publication date

1 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

Thrombosis and Haemostasis

25 January 2020

published in

1 reference

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25 January 2020

volume

101

1 reference

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25 January 2020

issue

4

1 reference

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25 January 2020

page(s)

724-733

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

Activated protein C-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin

25 January 2020

cites work

1 reference

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'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage

22 May 2018

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Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

22 May 2018

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The cytoprotective protein C pathway

22 May 2018

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Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells.

22 May 2018

1 reference

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Intravenous administration of activated protein C in Pseudomonas-induced lung injury: impact on lung fluid balance and the inflammatory response

22 May 2018

1 reference

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Roles of protease-activated receptors in a mouse model of endotoxemia

22 May 2018

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Protease-activated receptors-1 and -2 can mediate endothelial barrier protection: role in factor Xa signaling

22 May 2018

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Effects of recombinant human activated protein C in human models of endotoxin administration

22 May 2018

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Regulation of blood coagulation by the protein C anticoagulant pathway: novel insights into structure-function relationships and molecular recognition

22 May 2018

1 reference

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Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

22 May 2018

1 reference

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A role for proteinase-activated receptor-1 in inflammatory bowel diseases

22 May 2018

1 reference

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In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights

22 May 2018

1 reference

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Endothelial cell barrier regulation by sphingosine 1-phosphate

22 May 2018

1 reference

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Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3

22 May 2018

1 reference

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Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.

22 May 2018

1 reference

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Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

22 May 2018

1 reference

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PARticipation in inflammation

22 May 2018

1 reference

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Activation of endothelial cell protease activated receptor 1 by the protein C pathway

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680237

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

22 May 2018

1 reference

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LPS induction of gene expression in human monocytes

22 May 2018

1 reference

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Efficacy and safety of recombinant human activated protein C for severe sepsis

22 May 2018

1 reference

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Thrombin signalling and protease-activated receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680237

Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680237

Permanent cell line expressing human factor VIII-related antigen established by hybridization

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680237

Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680237

Limited generation of activated protein C during infusion of the protein C activator thrombin analog W215A/E217A in primates.

14 August 2018

1 reference

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Pathophysiological consequences of VEGF-induced vascular permeability

14 August 2018

1 reference

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Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin.

14 August 2018

1 reference

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Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling

14 August 2018

1 reference

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Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation

14 August 2018

1 reference

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Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury

14 August 2018

1 reference

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Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

14 August 2018

1 reference

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Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model.

14 August 2018

1 reference

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Rational design of a potent anticoagulant thrombin

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19350118

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Protein C Pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19350118

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tissue factor deficiency and PAR-1 deficiency are protective against renal ischemia reperfusion injury

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19350118

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1160/TH08-10-0632

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19350118%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference