Reactions catalyzed by mature and recombinant nonribosomal peptide synthetases. (Q51636993)

8 April 2018

title

Reactions catalyzed by mature and recombinant nonribosomal peptide synthetases. (English)

1 reference

8 April 2018

author name string

Uwe Linne

series ordinal

1

1 reference

8 April 2018

Mohamed A Marahiel

series ordinal

2

1 reference

8 April 2018

language of work or name

English

0 references

publication date

1 January 2004

1 reference

8 April 2018

published in

Methods in Enzymology

1 reference

8 April 2018

volume

388

1 reference

8 April 2018

page(s)

293-315

1 reference

8 April 2018

Nonribosomal peptides: from genes to products

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Multimodular biocatalysts for natural product assembly.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Biochemical characterization of peptidyl carrier protein (PCP), the thiolation domain of multifunctional peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

A new enzyme superfamily - the phosphopantetheinyl transferases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Peptide bond formation in nonribosomal peptide biosynthesis. Catalytic role of the condensation domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Ways of assembling complex natural products on modular nonribosomal peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Gramicidin S synthetase 1 (phenylalanine racemase), a prototype of amino acid racemases containing the cofactor 4'-phosphopantetheine.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Portability of epimerization domain and role of peptidyl carrier protein on epimerization activity in nonribosomal peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

The nonribosomal peptide synthetase HMWP2 forms a thiazoline ring during biogenesis of yersiniabactin, an iron-chelating virulence factor of Yersinia pestis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Expression, purification, and characterization of HMWP2, a 229 kDa, six domain protein subunit of Yersiniabactin synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Biosynthesis of cyclosporin A: partial purification and properties of a multifunctional enzyme from Tolypocladium inflatum

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Genes encoding synthetases of cyclic depsipeptides, anabaenopeptilides, in Anabaena strain 90.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Harnessing the biosynthetic code: combinations, permutations, and mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Decreasing the ring size of a cyclic nonribosomal peptide antibiotic by in-frame module deletion in the biosynthetic genes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Cloning and heterologous expression of the epothilone gene cluster.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Complete nucleotide sequence of the tycA gene coding the tyrocidine synthetase 1 from Bacillus brevis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Heterologous expression of nonribosomal peptide synthetases in B. subtilis: construction of a bi-functional B subtilis/E coli shuttle vector system

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

In vivo production of artificial nonribosomal peptide products in the heterologous host Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Dipeptide formation on engineered hybrid peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Loading peptidyl-coenzyme A onto peptidyl carrier proteins: a novel approach in characterizing macrocyclization by thioesterase domains

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Chirality of Peptide Bond-Forming Condensation Domains in Nonribosomal Peptide Synthetases: The C5 Domain of Tyrocidine Synthetase Is a DCL Catalyst

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Mutational analysis of the C-domain in nonribosomal peptide synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Systematic and Quantitative Analysis of Protein−Protein Recognition between Nonribosomal Peptide Synthetases Investigated in the Tyrocidine Biosynthetic Template

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Control of directionality in nonribosomal peptide synthesis: role of the condensation domain in preventing misinitiation and timing of epimerization

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Learning from nature's drug factories: nonribosomal synthesis of macrocyclic peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

The thioesterase domain from a nonribosomal peptide synthetase as a cyclization catalyst for integrin binding peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Biomimetic synthesis and optimization of cyclic peptide antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Chemoenzymatic route to macrocyclic hybrid peptide/polyketide-like molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Exploitation of the selectivity-conferring code of nonribosomal peptide synthetases for the rational design of novel peptide antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Rational design of peptide antibiotics by targeted replacement of bacterial and fungal domains

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Aminoacyl-CoAs as probes of condensation domain selectivity in nonribosomal peptide synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Construction of hybrid peptide synthetases by module and domain fusions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Engineering of peptide synthetases. Key role of the thioesterase-like domain for efficient production of recombinant peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Timing of epimerization and condensation reactions in nonribosomal peptide assembly lines: kinetic analysis of phenylalanine activating elongation modules of tyrocidine synthetase B.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Construction and in vitro analysis of a new bi-modular polypeptide synthetase for synthesis of N-methylated acyl peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Modification of biologically active peptides: production of a novel lipohexapeptide after engineering of Bacillus subtilis surfactin synthetase.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Intermodular communication in polyketide synthases: comparing the role of protein-protein interactions to those in other multidomain proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Antibiotic glycosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988024-8

7 January 2021

10.1016/S0076-6879(04)88024-8

Identifiers

DOI

1 reference

8 April 2018

PubMed ID

15289079

1 reference

8 April 2018