Fasting proinsulin levels are significantly associated with 20 year cancer mortality rates. The Hoorn Study. (Q51343811)

3 April 2018

title

Fasting proinsulin levels are significantly associated with 20 year cancer mortality rates. The Hoorn Study. (English)

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7

G Nijpels

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Jacqueline M Dekker

6

object named as

J M Dekker

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Coenraad Dirk Adriaan Stehouwer

3

object named as

C D A Stehouwer

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author name string

I Walraven

1

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3 April 2018

E van 't Riet

2

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B C P Polak

4

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A C Moll

5

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publication date

5 March 2013

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3 April 2018

published in

Diabetologia

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volume

56

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3 April 2018

issue

5

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page(s)

1148-1154

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3 April 2018

Meta-analysis of trial data may support a causal role of hyperglycaemia in cancer

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Fasting proinsulin concentrations predict the development of type 2 diabetes.

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Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway.

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Proinsulin concentration is an independent predictor of all-cause and cardiovascular mortality: an 11-year follow-up of the Hoorn Study

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Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn Study

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Fasting proinsulin and 2-h post-load glucose levels predict the conversion to NIDDM in subjects with impaired glucose tolerance: the Hoorn Study.

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Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults

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A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer

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Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn Study.

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10.1007/S00125-013-2864-6

Identifiers

DOI

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3 April 2018

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3 April 2018