PAS kinase is a nutrient and energy sensor in hypothalamic areas required for the normal function of AMPK and mTOR/S6K1. (Q51328251)

3 April 2018

title

PAS kinase is a nutrient and energy sensor in hypothalamic areas required for the normal function of AMPK and mTOR/S6K1. (English)

1 reference

3 April 2018

Carmen Sanz

6

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Elvira Alvarez

object named as

Elvira Alvarez

7

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Enrique Blazquez

object named as

Enrique Blazquez

5

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author name string

Verónica Hurtado-Carneiro

1

1 reference

3 April 2018

Isabel Roncero

2

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3 April 2018

Sascha S Egger

3

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3 April 2018

Roland H Wenger

4

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3 April 2018

publication date

21 January 2014

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3 April 2018

published in

Molecular Neurobiology

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3 April 2018

volume

50

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3 April 2018

issue

2

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3 April 2018

page(s)

314-326

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3 April 2018

https://scigraph.springernature.com/pub.10.1007/s12035-013-8630-4

exact match

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cites work

The role of PAS kinase in regulating energy metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

The PAS-domain kinase PASKIN: a new sensor in energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Regulation of glucose partitioning by PAS kinase and Ugp1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Yeast PAS kinase coordinates glucose partitioning in response to metabolic and cell integrity signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

PAS kinase is required for normal cellular energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMPK: a nutrient and energy sensor that maintains energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

New insights into mTOR signaling: mTORC2 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Regulation of mammalian translation factors by nutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Regulation of translation initiation by FRAP/mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

TSC2 mediates cellular energy response to control cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Hypothalamic mTOR signaling regulates food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

PAS kinase as a nutrient sensor in neuroblastoma and hypothalamic cells required for the normal expression and activity of other cellular nutrient and energy sensors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Glucagon-like peptide 1 (GLP-1) can reverse AMP-activated protein kinase (AMPK) and S6 kinase (P70S6K) activities induced by fluctuations in glucose levels in hypothalamic areas involved in feeding behaviour.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMP-activated protein kinase signaling in metabolic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Critical role for hypothalamic mTOR activity in energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Hypothalamic mTOR signaling mediates the orexigenic action of ghrelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMP-activated protein kinase plays a role in the control of food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMPK: Lessons from transgenic and knockout animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8630-4

Glucose-stimulated insulin production in mice deficient for the PAS kinase PASKIN

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24445950

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24445950

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12035-013-8630-4

1 reference

3 April 2018

PubMed ID

24445950

1 reference

3 April 2018