APOC3 Protein Is Not a Predisposing Factor for Fat-induced Nonalcoholic Fatty Liver Disease in Mice. (Q51172839)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28115523%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

title

APOC3 Protein Is Not a Predisposing Factor for Fat-induced Nonalcoholic Fatty Liver Disease in Mice (English)

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10 April 2020

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metabolic dysfunction–associated steatotic liver disease

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8

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10 April 2020

author name string

Xiaoyun Cheng

1

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10 April 2020

Jun Yamauchi

2

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10 April 2020

Sojin Lee

3

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10 April 2020

Ting Zhang

4

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10 April 2020

Zhenwei Gong

5

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10 April 2020

Radhika Muzumdar

6

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10 April 2020

Shen Qu

7

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10 April 2020

language of work or name

English

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publication date

23 January 2017

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Journal of Biological Chemistry

10 April 2020

published in

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10 April 2020

volume

292

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10 April 2020

issue

9

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10 April 2020

page(s)

3692-3705

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Targeting ApoC-III to Reduce Coronary Disease Risk

10 April 2020

cites work

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Abdominal fat interacts with PNPLA3 I148M, but not with the APOC3 variant in the pathogenesis of liver steatosis in chronic hepatitis C.

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Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans

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Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance

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Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia

22 May 2018

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22 May 2018

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Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism

22 May 2018

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22 May 2018

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Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.

22 May 2018

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Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice

22 May 2018

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22 May 2018

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Disruption of IRS-2 causes type 2 diabetes in mice

22 May 2018

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Apolipoprotein C-III gene variation and dyslipidaemia

22 May 2018

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Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E

22 May 2018

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Targeted disruption of the apolipoprotein C-III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia

22 May 2018

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Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III

22 May 2018

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Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles

22 May 2018

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Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase

22 May 2018

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A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.

22 May 2018

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Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes

14 August 2018

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Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics.

14 August 2018

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ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression

14 August 2018

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Apolipoprotein C3 deficiency results in diet-induced obesity and aggravated insulin resistance in mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5339753

Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensit

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5339753

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5339753

Transcriptional regulation of the apoC-III gene by insulin in diabetic mice: correlation with changes in plasma triglyceride levels

14 August 2018

1 reference

12 December 2020

Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice

1 reference

12 December 2020

Common genomic variation in the APOC3 promoter associated with variation in plasma lipoproteins

1 reference

12 December 2020

Plasma levels of remnant particles are determined in part by variation in the APOC3 gene insulin response element and the APOCI-APOE cluster

1 reference

12 December 2020

The effect of human C apolipoproteins on the in vitro hepatic metabolism of triglyceride emulsions in the rat

1 reference

12 December 2020

Pathology of nonalcoholic fatty liver disease

1 reference

12 December 2020

The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver

1 reference

12 December 2020

Inhibition of lipoprotein lipase activity by synthetic peptides of apolipoprotein C-III

1 reference

12 December 2020

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects

1 reference

12 December 2020

Alanine aminotransferase levels and fatty liver in childhood obesity: associations with insulin resistance, adiponectin, and visceral fat

1 reference

12 December 2020

Inhibitory effects of specific apolipoprotein C-III isoforms on the binding of triglyceride-rich lipoproteins to the lipolysis-stimulated receptor

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M116.765917

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28115523%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28115523%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

PubMed publication ID

28115523

1 reference