PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells. (Q50972583)

26 March 2018

title

PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells. (English)

1 reference

26 March 2018

author

Gregory Fairn

7

1 reference

26 March 2018

author name string

L Sun

1

1 reference

26 March 2018

Y Shi

2

1 reference

26 March 2018

G Wang

3

1 reference

26 March 2018

X Wang

4

1 reference

26 March 2018

S Zeng

5

1 reference

26 March 2018

S E Dunn

6

1 reference

26 March 2018

Y-J Li

8

1 reference

26 March 2018

D E Spaner

9

1 reference

26 March 2018

publication date

30 May 2017

1 reference

26 March 2018

published in

Leukemia

1 reference

26 March 2018

volume

32

1 reference

26 March 2018

page(s)

184-193

1 reference

26 March 2018

issue

1

1 reference

26 March 2018

https://scigraph.springernature.com/pub.10.1038/leu.2017.162

exact match

0 references

cites work

PPAR-alpha is a therapeutic target for chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

PPARs and lipid ligands in inflammation and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

PPAR-delta promotes survival of breast cancer cells in harsh metabolic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Transcriptional network governing the angiogenic switch in human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

PPARδ promotes oncogenic redirection of TGF-β1 signaling through the activation of the ABCA1-Cav1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Fluorescent Detection of Lipid Droplets and Associated Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Activity of the Janus kinase inhibitor ruxolitinib in chronic lymphocytic leukemia: results of a phase II trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

PPARgene: A Database of Experimentally Verified and Computationally Predicted PPAR Target Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Lentiviral vectors and transduction of human cancer B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Effect of serum and antioxidants on the immunogenicity of protein kinase C-activated chronic lymphocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Serum contains a platelet-derived transforming growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Cholesterol manipulation by West Nile virus perturbs the cellular immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Evidence that peroxisome proliferator-activated receptor delta influences cholesterol metabolism in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

ONCOMINE: a cancer microarray database and integrated data-mining platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

(Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): an orally bioavailable PPARβ/δ-selective ligand with inverse agonistic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Toll-like receptor-7 tolerizes malignant B cells and enhances killing by cytotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Active membrane cholesterol as a physiological effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Membrane cholesterol and the regulation of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Molecular Pathways: Dietary Regulation of Stemness and Tumor Initiation by the PPAR-δ Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Molecular regulation of HDL metabolism and function: implications for novel therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

ATP-citrate lyase: a key player in cancer metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

The molecular basis for functional plasticity in type I interferon signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

PPARδ activation acts cooperatively with 3-phosphoinositide-dependent protein kinase-1 to enhance mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

AKT/PKB Signaling: Navigating the Network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-δ/β overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

7 January 2021

PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

7 January 2021

Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

7 January 2021

Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2017.162

7 January 2021

Identifiers

DOI

10.1038/LEU.2017.162

1 reference

26 March 2018

PubMed ID

28555083

1 reference

26 March 2018