Thymoquinone-induced reactive oxygen species causes apoptosis of chondrocytes via PI3K/Akt and p38kinase pathway. (Q50890116)

24 March 2018

title

Thymoquinone-induced reactive oxygen species causes apoptosis of chondrocytes via PI3K/Akt and p38kinase pathway. (English)

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24 March 2018

main subject

reactive oxygen species

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Seon-Mi Yu

1

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24 March 2018

Song-Ja Kim

series ordinal

2

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24 March 2018

publication date

20 June 2013

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24 March 2018

Experimental Biology and Medicine

published in

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24 March 2018

volume

238

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24 March 2018

issue

7

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24 March 2018

page(s)

811-820

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24 March 2018

https://api.crossref.org/works/10.1177%2F1535370213492685

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Chondrocyte apoptosis: a cause or consequence of osteoarthritis?

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Cellular mechanisms for the repression of apoptosis.

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Mitochondrial functions during cell death, a complex (I–V) dilemma

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Reactive oxygen species and peroxisomes: struggling for balance

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The role of mitochondria in osteoarthritis

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Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes

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Role of quinones in toxicology.

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Reactive oxygen species, cellular redox systems, and apoptosis

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Mitochondrial formation of reactive oxygen species

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Mitochondrial metabolism of reactive oxygen species.

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Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions

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Ros-induced histone modifications and their role in cell survival and cell death.

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Mitochondria and apoptosis

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Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells.

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The anticancer drug cisplatin induces an intrinsic apoptotic pathway inside the inner ear.

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Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells

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Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells

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Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling

21 January 2018

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Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress

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Endogenous oxidative stress in sporadic Alzheimer's disease neuronal cybrids reduces viability by increasing apoptosis through pro-death signaling pathways and is mimicked by oxidant exposure of control cybrids

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The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation

21 January 2018

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The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells

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Oral RKS262 reduces tumor burden in a neuroblastoma xenograft animal model and mediates cytotoxicity through SAPK/JNK and ROS activation in vitro.

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Regulation and measurement of oxidative stress in apoptosis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/1535370213492685

1 reference

24 March 2018

1 reference

24 March 2018