Natural potent androgens: lessons from human genetic models. (Q50847801)

23 March 2018

review article

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title

Natural potent androgens: lessons from human genetic models. (English)

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23 March 2018

Julianne Imperato-McGinley

author

series ordinal

3

object named as

Imperato-McGinley J

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23 March 2018

author name string

Zhu YS

series ordinal

1

1 reference

23 March 2018

Katz MD

series ordinal

2

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23 March 2018

publication date

1 April 1998

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23 March 2018

Bailliere's clinical endocrinology and metabolism

published in

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23 March 2018

volume

12

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23 March 2018

issue

1

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23 March 2018

page(s)

83-113

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23 March 2018

Molecular cloning of a novel widely expressed human 80 kDa 17 beta-hydroxysteroid dehydrogenase IV

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Selective Retention of Dihydrotestosterone by Prostatic Nuclei

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Physiology and molecular genetics of 17 beta-hydroxysteroid dehydrogenases

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17β-Hydroxysteroid dehydrogenase 3 deficiency

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Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

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Prepubertal male pseudohermaphroditism due to 17-ketosteroid reductase deficiency: diagnostic value of a hCG test and lack of HLA association

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Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol

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Gene regulation by steroid hormones

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The development of human benign prostatic hyperplasia with age

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The metabolism of testosterone by human male scalp skin.

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Prostate volume predicts outcome of treatment of benign prostatic hyperplasia with finasteride: Meta-analysis of randomized clinical trials

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Hypothyroid-like alterations in testosterone metabolism in anorexia nervosa

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Kinetic parameters of 5 alpha-reductase activity in stroma and epithelium of normal, hyperplastic, and carcinomatous human prostates.

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7 January 2021

5 alpha-reductase-2 gene mutations in the Dominican Republic

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7 January 2021

The Identification of 5 -Reductase-2 and 17 -Hydroxysteroid Dehydrogenase-3 Gene Defects in Male Pseudohermaphrodites from a Turkish Kindred

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7 January 2021

Mutations of the 5 alpha-reductase type 2 gene in eight Mexican patients from six different pedigrees with 5 alpha-reductase-2 deficiency.

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Variable expression of 5 alpha-reductase deficiency: presentation with male phenotype in a child of Greek origin

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Male hypogonadism with gynecomastia caused by late-onset deficiency of testicular 17-ketosteroid reductase

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7 January 2021

Opposite Effects of Dexamethasone on Serum Concentrations of 3, 3′,5′-Triiodothyronine (Reverse T3) and 3,3′,5′-Triiodothyronine (T3)

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7 January 2021

Clinical and endocrine effects of finasteride, a 5 alpha-reductase inhibitor, in women with idiopathic hirsutism

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7 January 2021

The CpG dinucleotide and human genetic disease

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7 January 2021

Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque

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7 January 2021

The nature of the defect in familial male pseudohermaphroditism in Arabs of Gaza

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7 January 2021

Immunocytochemical localization of human 5 alpha-reductase 2 with polyclonal antibodies in androgen target and non-target human tissues

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7 January 2021

Immunohistochemical evidence for differential distribution of 5 alpha-reductase isoenzymes in human skin

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7 January 2021

Decreased 3 alpha-androstanediol glucuronide levels in plasma and random urines in male pseudohermaphroditism caused by 5 alpha-reductase deficiency

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7 January 2021

Finasteride: a slow-binding 5 alpha-reductase inhibitor.

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Finasteride (MK-906) in the treatment of benign prostatic hyperplasia. The Finasteride Study Group

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7 January 2021

Clinical, Endocrinological, and Enzymatic Characterization of Two Patients with 5α-Reductase Deficiency: Evidence that a Single Enzyme Is Responsible for the 5α-Reduction of Cortisol and Testosterone*

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7 January 2021

Steroid 5 alpha-reductase 2 deficiency: virilization in early infancy may be due to partial function of mutant enzyme.

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7 January 2021

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

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7 January 2021

Effect of long-acting gonadotropin-releasing hormone analog (leuprolide) therapy on prostatic size and symptoms in 15 men with benign prostatic hypertrophy

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7 January 2021

Isolation and sequencing of a complementary deoxyribonucleic acid clone encoding human placental 17 beta-estradiol dehydrogenase: identification of the putative cofactor binding site

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Male pseudohermaphroditism caused by mutations of testicular 17 beta-hydroxysteroid dehydrogenase 3

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7 January 2021

Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution

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7 January 2021

Effects of perinatal androstenedione on sexual behavior differentiation in male rats

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7 January 2021

Familial male pseudohermaphroditism without gynecomastia due to deficient testicular 17-ketosteroid reductase activity

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7 January 2021

In VitroSteroid Metabolic Studies in Testicular 17β-Reduction Deficiency

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7 January 2021

Male pseudohermaphroditism due to testicular 17 -hydroxysteroid dehydrogenase deficiency

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7 January 2021

The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group

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7 January 2021

Male pseudohermaphroditism due to 17 beta-hydroxysteroid dehydrogenase deficiency: gender reassignment in early infancy

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7 January 2021

Androstenedione production and interconversion rates measured in peripheral blood and studies on the possible site of its conversion to testosterone

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7 January 2021

Comparison of nuclear 5 alpha-reductase activities in the stromal and epithelial fractions of human prostatic tissue

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7 January 2021

Male pseudohermaphroditism: The complexities of male phenotypic development

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7 January 2021

C19and C215β/5αMetabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency*

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7 January 2021

Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism

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7 January 2021

Male pseudohermaphroditism secondary to 5α-reductase deficiency—A model for the role of androgens in both the development of the male phenotype and the evolution of a male gender identity

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7 January 2021

Androgens and the Evolution of Male-Gender Identity among Male Pseudohermaphrodites with 5α-Reductase Deficiency

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7 January 2021

Male Pseudohermaphroditism Secondary to 17β-Hydroxysteroid Dehydrogenase Deficiency: Gender Role Change with Puberty*

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7 January 2021

Steroid 5 alpha-reductase deficiency in a 65-year-old male pseudohermaphrodite: the natural history, ultrastructure of the testes, and evidence for inherited enzyme heterogeneity

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7 January 2021

Hormonal evaluation of a large kindred with complete androgen insensitivity: evidence for secondary 5 alpha-reductase deficiency

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7 January 2021

The development of a male pseudohermaphroditic rat using an inhibitor of the enzyme 5 alpha-reductase

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7 January 2021

The coexistence of male pseudohermaphrodites with 17-ketosteroid reductase deficiency and 5 alpha-reductase deficiency within a Turkish kindred

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7 January 2021

A cluster of male pseudohermaphrodites with 5α-reductase deficiency in Papua New Guinea

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7 January 2021

Characterization of 5 alpha-reductase in cultured human dermal papilla cells from beard and occipital scalp hair

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7 January 2021

5-alpha reductase deficient men are fertile

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7 January 2021

Male pseudohermaphroditism due to 5?-reductase deficiency in a Swedish family

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Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase

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Partial androgen resistance associated with secondary 5 alpha-reductase deficiency: identification of a novel qualitative androgen receptor defect and clinical implications

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7 January 2021

Studies in porphyria. I. A defect in the reductive transformation of natural steroid hormones in the hereditary liver disease, acute intermittent porphyria

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Paternity by intrauterine insemination with sperm from a man with 5alpha-reductase-2 deficiency.

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7 January 2021

Plasma testosterone in male puberty. I. Physiology of plasma testosterone.

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Male development of chromosomally female mice transgenic for Sry.

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A mutation that causes lability of the androgen receptor under conditions that normally promote transformation to the DNA-binding state

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7 January 2021

Androgen production and skin metabolism in hirsutism

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7 January 2021

Male Pseudohermaphroditism: A Comparative Study of One Patient with 5α-Reductase Deficiency and Three Patients with the Complete Form of Testicular Feminization*

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7 January 2021

Structure of human type II 5 alpha-reductase gene

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The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology

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7 January 2021

Species differences in prostatic steroid 5 alpha-reductases of rat, dog, and human

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7 January 2021

A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.

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7 January 2021

Characterization of cDNAs for human estradiol 17 beta-dehydrogenase and assignment of the gene to chromosome 17: evidence of two mRNA species with distinct 5'-termini in human placenta

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7 January 2021

Immunohistochemical study of the human 17 beta-hydroxysteroid dehydrogenase and steroid receptors in endometrial adenocarcinoma

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7 January 2021

Male pseudohermaphroditism due to steroid 5alpha-reductase 2 deficiency. Diagnosis, psychological evaluation, and management.

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Androgen binding capacity and 5 alpha-reductase activity in pubic skin fibroblasts from hirsute patients

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Aromatization of androstenedione by limbic system tissue from human foetuses.

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Aromatization of Androstenedione by the Anterior Hypothalamus of Adult Male and Female Rats

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7 January 2021

5 alpha-reductase deficiency without hypospadias

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7 January 2021

Masculinization of the female golden hamster by neonatal treatment with androgen or estrogen

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7 January 2021

Complete amino acid sequence of human placental 17 beta-hydroxysteroid dehydrogenase deduced from cDNA.

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7 January 2021

Male pseudohermaphroditism due to steroid 5-alpha-reductase deficiency

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7 January 2021

Urinary steroid metabolites in subjects with male pseudohermaphroditism due to 5 alpha-reductase deficiency.

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7 January 2021

Immunological analysis of 17β-hydroxysteroid dehydrogenase in benign and malignant human breast tissue

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7 January 2021

High dose androgen therapy in male pseudohermaphroditism due to 5 alpha-reductase deficiency and disorders of the androgen receptor

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7 January 2021

Conversion of androstenedione to estrone by neural tissues from fetal and neonatal rats.

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7 January 2021

Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency: Studies on the natural history of the defect and effect of androgens on gender role

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7 January 2021

Prepubertal diagnosis of steroid 5 alpha-reductase deficiency

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7 January 2021

Further in vivo studies in male pseudohermaphroditism with gynecomastia due to a testicular 17-ketosteroid reductase defect (compared to a case of testicular feminization)

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7 January 2021

Familial male pseudohermaphroditism with gynecomastia due to a testicular 17-ketosteroid reductase defect. I. Studies in vivo

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7 January 2021

Familial male pseudohermaphroditism due to deficiency of 5 alpha-reductase

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7 January 2021

Male Pseudohermaphroditism Due to Testicular 17-Ketosteroid Reductase Deficiency

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7 January 2021

Management of urinary retention due to benign prostatic hyperplasia using luteinizing hormone-releasing hormone agonist

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7 January 2021

17-ketosteroid reductase deficiency -- plasma steroids and incubation studies with testicular tissue

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7 January 2021

Altered major histocompatibility complex-restricted antigen recognition by T cells from elderly humans

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7 January 2021

Regulation of Human Hair Growth by Steroid Hormones. I. Testosterone Metabolism in Isolated Hairs

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7 January 2021

5 alpha-Reductase activity in the genital skin of hirsute women

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7 January 2021

Testosterone formation and metabolism during male sexual differentiation in the human embryo

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7 January 2021

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

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7 January 2021

Flutamide in treatment of benign prostatic hypertrophy.

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7 January 2021

Brief report: the molecular basis of steroid 5 alpha-reductase deficiency in a large Dominican kindred

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7 January 2021

Molecular genetics of steroid 5 alpha-reductase 2 deficiency

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7 January 2021

Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression

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7 January 2021

Endocrine and biochemical studies in a 46,XY phenotypically male infant with 17-ketosteroid reductase deficiency

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7 January 2021

Endocrine studies in a pubertal male pseudohermaphrodite with 17-ketosteroid reductase deficiency

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7 January 2021

Familial incomplete male pseudohermaphroditism, type 2. Decreased dihydrotestosterone formation in pseudovaginal perineoscrotal hypospadias.

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7 January 2021

Inhibition of lordosis in female rats by subcutaneous implants of testosterone, androstenedione or dihydrotestosterone in infancy

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7 January 2021

I. The Results of Double Castration in Hypertrophy of the Prostate

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7 January 2021

Natural Mutagenesis Study of the Human Steroid 5.alpha.-Reductase 2 Isoenzyme

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7 January 2021

Characterization of the Cytosol Androgen Receptor of the Human Prostate*

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7 January 2021

10.1016/S0950-351X(98)80478-3

Identifiers

DOI

1 reference

23 March 2018

PubMed ID

9890063

1 reference

23 March 2018