Aldehyde dehydrogenase 1 activity in the developing human pancreas modulates retinoic acid signalling in mediating islet differentiation and survival. (Q50699491)

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scientific article published on 28 December 2013

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English	Aldehyde dehydrogenase 1 activity in the developing human pancreas modulates retinoic acid signalling in mediating islet differentiation and survival.	scientific article published on 28 December 2013

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3 March 2020

Aldehyde dehydrogenase 1 activity in the developing human pancreas modulates retinoic acid signalling in mediating islet differentiation and survival (English)

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3 March 2020

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Jinming Li

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Zhi C Feng

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Frances S-H Yeung

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Melanie R-M Wong

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George F Fellows

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Cynthia G Goodyer

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David A Hess

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Rennian Wang

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28 December 2013

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57

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3 March 2020

https://scigraph.springernature.com/pub.10.1007/s00125-013-3147-y

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Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

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21 January 2018

Moving forward in human mammary stem cell biology and breast cancer prognostication using ALDH1.

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21 January 2018

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

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21 January 2018

Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells

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21 January 2018

Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity.

1 reference

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21 January 2018

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity

1 reference

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21 January 2018

Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor

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21 January 2018

Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples

1 reference

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21 January 2018

Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity.

1 reference

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21 January 2018

Evaluation of mobilized peripheral stem cells according to CD34 and aldehyde dehydrogenase expression and effect of SSC(lo) ALDH(br) cells on hematopoietic recovery.

1 reference

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21 January 2018

High aldehyde dehydrogenase activity: a novel functional marker of murine prostate stem/progenitor cells

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21 January 2018

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity.

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21 January 2018

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

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21 January 2018

Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with pancreatic cancer

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21 January 2018

ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma

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21 January 2018

Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival

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21 January 2018

RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

All-trans retinoic acid suppresses exocrine differentiation and branching morphogenesis in the embryonic pancreas

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

Transcription factor expression in the developing human fetal endocrine pancreas.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

Effect of forkhead box O1 (FOXO1) on beta cell development in the human fetal pancreas

1 reference

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21 January 2018

DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex

1 reference

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21 January 2018

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS.

1 reference

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21 January 2018

Expression of the receptor tyrosine kinase KIT in mature beta-cells and in the pancreas in development

1 reference

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21 January 2018

Prominin-1 (CD133) Reveals New Faces of Pancreatic Progenitor Cells and Cancer Stem Cells: Current Knowledge and Therapeutic Perspectives

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21 January 2018

In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells

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21 January 2018

The function of e-cadherin in stem cell pluripotency and self-renewal

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21 January 2018

The expression of the class 1 glucose transporter isoforms in human embryonic stem cells, and the potential use of GLUT2 as a marker for pancreatic progenitor enrichment

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

Beta cell differentiation during early human pancreas development.

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https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

SOX9 is required for maintenance of the pancreatic progenitor cell pool

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

SOX9 regulates endocrine cell differentiation during human fetal pancreas development.

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21 January 2018

Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3147-Y

21 January 2018

Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms.

1 reference

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21 January 2018

The role of retinoids and retinoic acid receptors in normal hematopoiesis

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21 January 2018

Requirement of retinoic acid receptor isotypes alpha, beta, and gamma during the initial steps of neural differentiation of PCC7 cells

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21 January 2018

Retinoic acid synthesis and signaling during early organogenesis

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21 January 2018

Vitamin D and vitamin A receptor expression and the proliferative effects of ligand activation of these receptors on the development of pancreatic progenitor cells derived from human fetal pancreas

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21 January 2018

Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation

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21 January 2018

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

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12 December 2020

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Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells

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https://pubmed.ncbi.nlm.nih.gov/24374552

12 December 2020

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Differentiation of Affinity-Purified Human Pancreatic Duct Cells to -Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24374552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24374552

12 December 2020

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inferred from PubMed ID database lookup

Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/24374552

12 December 2020

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Expression of c-Kit receptor tyrosine kinase and effect on beta-cell development in the human fetal pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24374552

12 December 2020

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inferred from PubMed ID database lookup

4-Hydroxybenzyl modification of the highly teratogenic retinoid, 4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)-1-propen-1-yl]benzoic acid (TTNPB), yields a compound that induces apoptosis in breast cancer cells and shows reduced

1 reference

https://pubmed.ncbi.nlm.nih.gov/24374552

12 December 2020

based on heuristic

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Critical role of c-Kit in beta cell function: increased insulin secretion and protection against diabetes in a mouse model

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https://pubmed.ncbi.nlm.nih.gov/24374552

12 December 2020

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Dual action of retinoic acid on human embryonic/fetal hematopoiesis: blockade of primitive progenitor proliferation and shift from multipotent/erythroid/monocytic to granulocytic differentiation program

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https://pubmed.ncbi.nlm.nih.gov/24374552

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10.1007/S00125-013-3147-Y

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Europe PubMed Central

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3 March 2020

release_zj5uwh2whvda5egsavznnj3xjq

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24 November 2022

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3 March 2020

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