Reduced fertility of female mice lacking CD81. (Q50654180)

17 March 2018

title

Reduced fertility of female mice lacking CD81. (English)

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17 March 2018

author

Eric Rubinstein

1

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17 March 2018

Ahmed Ziyyat

object named as

Ahmed Ziyyat

2

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Claude Boucheix

object named as

Claude Boucheix

8

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author name string

Michel Prenant

3

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17 March 2018

Edyta Wrobel

4

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17 March 2018

Jean-Philippe Wolf

5

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Shoshana Levy

6

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17 March 2018

François Le Naour

7

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17 March 2018

language of work or name

English

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publication date

27 December 2005

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17 March 2018

published in

Developmental Biology

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17 March 2018

volume

290

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17 March 2018

page(s)

351-358

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issue

2

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17 March 2018

Infertility in female mice with an oocyte-specific knockout of GPI-anchored proteins

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Pre-loading of mouse oocytes with DNA-specific fluorochrome (Hoechst 33342) permits rapid detection of sperm-oocyte fusion

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Treatment of mouse oocytes with PI-PLC releases 70-kDa (pI 5) and 35- to 45-kDa (pI 5.5) protein clusters from the egg surface and inhibits sperm-oolemma binding and fusion

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None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion

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Severely reduced female fertility in CD9-deficient mice

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The tetraspanin web modulates immune-signalling complexes

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Normal lymphocyte development but delayed humoral immune response in CD81-null mice

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Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies

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Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infection

7 January 2021

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Normal fertilization occurs with eggs lacking the integrin alpha6beta1 and is CD9-dependent

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Antibodies to CD9, a tetraspan transmembrane protein, inhibit canine distemper virus-induced cell-cell fusion but not virus-cell fusion

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7 January 2021

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Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity

7 January 2021

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Sperm-egg fusion: events at the plasma membrane

7 January 2021

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Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes

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Characterization of mice lacking the tetraspanin superfamily member CD151

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Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration

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7 January 2021

Identifiers

DOI

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17 March 2018

PubMed ID

16380109

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17 March 2018