Molecular Docking Optimization in the Context of Multi-Drug Resistant and Sensitive EGFR Mutants. (Q50545253)

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27 March 2020

title

Molecular Docking Optimization in the Context of Multi-Drug Resistant and Sensitive EGFR Mutants (English)

1 reference

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27 March 2020

main subject

multiple drug resistance

1 reference

based on heuristic

inferred from title

author

María Jesús García-Godoy

1

1 reference

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27 March 2020

Esteban López-Camacho

2

1 reference

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27 March 2020

José García-Nieto

3

1 reference

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27 March 2020

Antonio J. Nebro

4

1 reference

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27 March 2020

author name string

José F Aldana-Montes

5

1 reference

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27 March 2020

language of work or name

English

0 references

publication date

19 November 2016

1 reference

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27 March 2020

1 reference

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27 March 2020

volume

21

1 reference

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27 March 2020

issue

11

1 reference

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Creative Commons Attribution 4.0 International

27 March 2020

copyright license

start time

19 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

1 reference

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Lung adenocarcinoma harboring L858R and T790M mutations in epidermal growth factor receptor, with poor response to gefitinib: A case report

21 January 2018

1 reference

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EADock: docking of small molecules into protein active sites with a multiobjective evolutionary optimization.

21 January 2018

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Solving molecular docking problems with multi-objective metaheuristics.

21 January 2018

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

21 January 2018

1 reference

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Comparative study of several algorithms for flexible ligand docking

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21111575

A fast and elitist multiobjective genetic algorithm: NSGA-II

21 January 2018

1 reference

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21 January 2018

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1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21111575

Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21111575

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21111575

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

21 January 2018

1 reference

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jMetalCpp: optimizing molecular docking problems with a C++ metaheuristic framework.

21 January 2018

1 reference

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UCSF Chimera--a visualization system for exploratory research and analysis

21 January 2018

1 reference

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Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed

21 January 2018

1 reference

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Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor

21 January 2018

1 reference

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Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

21 January 2018

1 reference

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Structural signature of the G719S-T790M double mutation in the EGFR kinase domain and its response to inhibitors.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27869781

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/MOLECULES21111575

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869781%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27869781%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

PubMed publication ID

27869781

1 reference