A 17-gene stemness score for rapid determination of risk in acute leukaemia. (Q50538514)

15 March 2018

title

A 17-gene stemness score for rapid determination of risk in acute leukaemia. (English)

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15 March 2018

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14

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Klaus H Metzeler

23

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Meyling H Cheok

Meyling Cheok

20

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Aaron Schimmer

Aaron D Schimmer

10

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John Dick

John E Dick

29

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Claude Preudhomme

Claude Preudhomme

21

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Hervé Dombret

22

Herve Dombret

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15 March 2018

25

Bob Löwenberg

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15 March 2018

Peter W Zandstra

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Peter W Zandstra

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15 March 2018

Weihsu C Chen

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Weihsu C Chen

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15 March 2018

Andre C Schuh

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Andre C Schuh

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15 March 2018

author name string

Stanley W K Ng

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15 March 2018

Amanda Mitchell

2

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James A Kennedy

3

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Jessica McLeod

5

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Narmin Ibrahimova

6

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Andrea Arruda

7

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Andreea Popescu

8

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Vikas Gupta

9

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Karen W Yee

12

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Lars Bullinger

13

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Dennis Görlich

15

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Thomas Büchner

16

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Wolfgang Hiddemann

17

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Wolfgang E Berdel

18

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Bernhard Wörmann

19

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15 March 2018

Christian Buske

24

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Peter J M Valk

26

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Mark D Minden

28

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Jean C Y Wang

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15 March 2018

language of work or name

English

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publication date

7 December 2016

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15 March 2018

published in

Nature

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15 March 2018

volume

540

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15 March 2018

page(s)

433-437

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15 March 2018

issue

7633

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15 March 2018

https://scigraph.springernature.com/pub.10.1038/nature20598

exact match

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cites work

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SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells

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BET inhibitor resistance emerges from leukaemia stem cells

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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

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Stem cell gene expression programs influence clinical outcome in human leukemia.

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Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice

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The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment

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Densely interconnected transcriptional circuits control cell states in human hematopoiesis

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Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

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Regularization Paths for Generalized Linear Models via Coordinate Descent

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Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent

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Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

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An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

21 January 2018

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Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance

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Genomic Classification and Prognosis in Acute Myeloid Leukemia

21 January 2018

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Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

21 January 2018

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Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.

21 January 2018

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An LSC epigenetic signature is largely mutation independent and implicates the HOXA cluster in AML pathogenesis

21 January 2018

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The European LeukemiaNet AML Working Party consensus statement on allogeneic HSCT for patients with AML in remission: an integrated-risk adapted approach

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Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways.

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Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study

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Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials

21 January 2018

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Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia

21 January 2018

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21 January 2018

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limma powers differential expression analyses for RNA-sequencing and microarray studies

21 January 2018

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21 January 2018

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21 January 2018

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Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

21 January 2018

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RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells

21 January 2018

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Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue

21 January 2018

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Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor specimens

21 January 2018

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Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

21 January 2018

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Investigation of the freely available easy-to-use software 'EZR' for medical statistics

21 January 2018

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Cox's Regression Model for Counting Processes: A Large Sample Study

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Long-term prognosis of acute myeloid leukemia according to the new genetic risk classification of the European LeukemiaNet recommendations: evaluation of the proposed reporting system

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27926740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE20598

1 reference

15 March 2018

PubMed ID

27926740

1 reference

15 March 2018