Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery (Q50525641)

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scientific article published on 4 March 2011

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English	Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery	scientific article published on 4 March 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

convection-enhanced delivery

0 references

author name string

E White

1

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

A Bienemann

2

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

L Megraw

3

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

C Bunnun

4

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

S Gill

5

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

publication date

4 March 2011

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

Cancer Gene Therapy

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

18

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

5

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

358-369

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

The interface between glial progenitors and gliomas

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Molecular pathology of malignant gliomas

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Malignant glioma: patterns of failure following individually tailored limited volume irradiation

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Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy

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HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival

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Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

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The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study

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The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

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Assessment of 123I-FIAU imaging of herpes simplex viral gene expression in the treatment of glioma.

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HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applications

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In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space

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Stable levels of long-term transgene expression driven by the latency-associated transcript promoter in a herpes simplex virus type 1 vector

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Bioluminescence imaging after HSV amplicon vector delivery into brain.

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Stable transgene expression from HSV amplicon vectors in the brain: potential involvement of immunoregulatory signals

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Dynamic of migration of HSV-1 from a medullary pronociceptive centre: antinociception by overexpression of the preproenkephalin transgene

1 reference

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Potential and limitations of a gamma 34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS.

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Drug inducible transgene expression in brain using a herpes simplex virus vector

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Latency associated promoter transgene expression in the central nervous system after stereotaxic delivery of replication-defective HSV-1-based vectors

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21 January 2018

A novel herpesvirus amplicon system for in vivo gene delivery

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21 January 2018

High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5.

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21 January 2018

Safety and biodistribution studies of an HSV multigene vector following intracranial delivery to non-human primates

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21 January 2018

Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model

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21 January 2018

Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy.

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21 January 2018

HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma

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Effective treatment of experimental glioblastoma by HSV vector-mediated TNF alpha and HSV-tk gene transfer in combination with radiosurgery and ganciclovir administration

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21 January 2018

HSV-1 amplicon-mediated post-transcriptional inhibition of Rad51 sensitizes human glioma cells to ionizing radiation

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21 January 2018

Quantitation of HSV mass distribution in a rodent brain tumor model.

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21 January 2018

Widespread correction of lysosomal storage in the mucopolysaccharidosis type VII mouse brain with a herpes simplex virus type 1 vector expressing beta-glucuronidase

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21 January 2018

A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease

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Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration

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Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease

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Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery

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Antibodies to CD11b, CD68, and lectin label neutrophils rather than microglia in traumatic and ischemic brain lesions

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Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans

1 reference

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Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain.

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Recombinant adeno-associated virus serotypes 2- and 5-mediated gene transfer in the mammalian brain: quantitative analysis of heparin co-infusion

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Surface properties, more than size, limiting convective distribution of virus-sized particles and viruses in the central nervous system

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Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating

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Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles.

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Convection-enhanced delivery of macromolecules in the brain

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Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus

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Epidemiology of primary brain tumors: current concepts and review of the literature

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7 January 2021

based on heuristic

inferred from DOI database lookup

Combination gene therapy for glioblastoma involving herpes simplex virus vector-mediated codelivery of mutant IkappaBalpha and HSV thymidine kinase

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based on heuristic

inferred from DOI database lookup

Initial interaction of herpes simplex virus with cells is binding to heparan sulfate

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CGT.2011.2

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/21372854

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