Slowing the progression of age-related hearing loss: Rationale and study design of the ASPIRIN in HEARING, retinal vessels imaging and neurocognition in older generations (ASPREE-HEARING) trial. (Q50317496)

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scientific article published on 20 November 2015

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English	Slowing the progression of age-related hearing loss: Rationale and study design of the ASPIRIN in HEARING, retinal vessels imaging and neurocognition in older generations (ASPREE-HEARING) trial.	scientific article published on 20 November 2015

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Slowing the progression of age-related hearing loss: Rationale and study design of the ASPIRIN in HEARING, retinal vessels imaging and neurocognition in older generations (ASPREE-HEARING) trial (English)

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Judy A Lowthian

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Jessica Lockery

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J E Lockery

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R L Woods

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E Storey

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C J Britt

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G Rance

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F R Lin

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M R Nelson

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S Ward

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C M Reid

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T T Nguyen

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ASPREE Investigators

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28 November 2015

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Contemporary Clinical Trials

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60-66

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1 March 2020

Increased proinflammatory cytokines in patients with chronic stable angina and their reduction by aspirin

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A High Plasma Concentration of TNF- Is Associated With Dementia in Centenarians

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12 December 2020

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Age-related hearing loss: current research

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The impact of hearing loss on quality of life in older adults

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Is retinal photography useful in the measurement of stroke risk?

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Post-exposure treatment attenuates noise-induced hearing loss

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https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

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Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects

1 reference

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12 December 2020

based on heuristic

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Proinflammatory cytokines expression in noise-induced damaged cochlea

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https://pubmed.ncbi.nlm.nih.gov/26611434

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Effect of aspirin plus clopidogrel on inflammatory markers in patients with non-ST-segment elevation acute coronary syndrome

1 reference

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Acceleration of age-related hearing loss by early noise exposure: evidence of a misspent youth

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12 December 2020

based on heuristic

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Aspirin to prevent gentamicin-induced hearing loss

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https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

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Regular aspirin use and retinal microvascular signs: the Blue Mountains Eye Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

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The clinical impact of systemic low-level inflammation in elderly populations. With special reference to cardiovascular disease, dementia and mortality.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Retinal microvascular abnormalities and age-related hearing loss: the Blue Mountains hearing study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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An assessment of the joint associations of aspirin and statin use with C-reactive protein concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

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Prevalence of hearing loss and differences by demographic characteristics among US adults: data from the National Health and Nutrition Examination Survey, 1999-2004.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

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Molecular inflammation: underpinnings of aging and age-related diseases

1 reference

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12 December 2020

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Vision and hearing impairments and their associations with falling and loss of instrumental activities in daily living in acute hospitalized older persons in five Nordic hospitals

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

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Mechanisms and genes in human strial presbycusis from animal models

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

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Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Three decade change in the prevalence of hearing impairment and its association with diabetes in the United States.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Can aspirin protect or at least attenuate gentamicin ototoxicity in humans?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Efficacy of different doses of aspirin in decreasing blood levels of inflammatory markers in patients with cardiovascular metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Potential mediators of diabetes-related hearing impairment in the U.S. population: National Health and Nutrition Examination Survey 1999-2004.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Analgesic use and the risk of hearing loss in men

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Associations between hearing impairment and mortality risk in older persons: the Blue Mountains Hearing Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Dosing study on the effectiveness of salicylate/N-acetylcysteine for prevention of noise-induced hearing loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Tumor necrosis factor-α enhances microvascular tone and reduces blood flow in the cochlea via enhanced sphingosine-1-phosphate signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory markers in population studies of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hearing loss prevalence and risk factors among older adults in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Hearing loss and cognition in the Baltimore Longitudinal Study of Aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Markers of inflammatory status are associated with hearing threshold in older people: findings from the Hertfordshire Ageing Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Severity of age-related hearing loss is associated with impaired activities of daily living.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Global and regional hearing impairment prevalence: an analysis of 42 studies in 29 countries

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Evaluating a dichotomized measure of self-reported hearing loss against gold standard audiometry: prevalence estimates and age bias in a pooled national data set.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Listening in Spatialized Noise-Sentences Test (LiSN-S): normative and retest reliability data for adolescents and adults up to 60 years of age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion).

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Cognitive, health, and sociodemographic predictors of longitudinal decline in hearing acuity among older adults.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Hearing-impaired adults are at increased risk of experiencing emotional distress and social engagement restrictions five years later.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analgesic use and the risk of hearing loss in women

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of hearing impairment and aging on spatial processing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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Central presbycusis: a review and evaluation of the evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk of developing sudden sensorineural hearing loss in diabetic patients: a population-based cohort study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hearing loss and cognitive decline in older adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

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Association of hearing loss with hospitalization and burden of disease in older adults.

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Long-term variability of inflammatory markers and associated factors in a population-based cohort

1 reference

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1 reference

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Dual sensory loss and depressive symptoms: the importance of hearing, daily functioning, and activity engagement.

1 reference

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Retinal microvascular abnormalities predict progression of brain microvascular disease: an atherosclerosis risk in communities magnetic resonance imaging study

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation is associated with a worsening of presbycusis: evidence from the MRC national study of hearing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

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based on heuristic

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Hearing loss and dementia - who is listening?

1 reference

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Progress and prospects in human genetic research into age-related hearing impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

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based on heuristic

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Emerging evidence for platelets as immune and inflammatory effector cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

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based on heuristic

inferred from PubMed ID database lookup

Concentration-response relationships for salicylate-induced ototoxicity in normal volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Modified Mini-Mental State (3MS) examination

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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The hearing handicap inventory for the elderly: a new tool

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

12 December 2020

based on heuristic

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A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

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Immunoglobulin deposition in thickened basement membranes of aging strial capillaries

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611434

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10.1016/J.CCT.2015.11.014

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1 March 2020

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1 March 2020

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1 March 2020

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