Randomised controlled trial of simvastatin treatment for autism in young children with neurofibromatosis type 1 (SANTA). (Q50301194)

30 June 2018

title

Randomised controlled trial of simvastatin treatment for autism in young children with neurofibromatosis type 1 (SANTA). (English)

1 reference

30 June 2018

Francisco Xavier Castellanos

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15

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30 June 2018

Stephen K Williams

18

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30 June 2018

Richard Emsley

20

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30 June 2018

Gareth Evans

object named as

D Gareth Evans

19

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author name string

Stavros Stivaros

1

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30 June 2018

Shruti Garg

2

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30 June 2018

Maria Tziraki

3

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30 June 2018

Ying Cai

4

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30 June 2018

Owen Thomas

5

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30 June 2018

Joseph Mellor

6

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30 June 2018

Andrew A Morris

7

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30 June 2018

Carly Jim

8

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30 June 2018

Karolina Szumanska-Ryt

9

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30 June 2018

Laura M Parkes

10

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30 June 2018

Hamied A Haroon

11

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30 June 2018

Daniela Montaldi

12

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30 June 2018

Nicholas Webb

13

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30 June 2018

John Keane

14

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30 June 2018

Alcino J Silva

16

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30 June 2018

Sue Huson

17

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30 June 2018

SANTA Consortium

22

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30 June 2018

publication date

22 February 2018

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30 June 2018

published in

Molecular Autism

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30 June 2018

volume

9

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30 June 2018

page(s)

12

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30 June 2018

describes a project that uses

scikit-image

1 reference

8 June 2022

https://europepmc.org/search?query=(METHODS:'scikit-image')

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/s13229-018-0190-z

0 references

cites work

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Randomized placebo-controlled study of lovastatin in children with neurofibromatosis type 1.

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3 July 2018

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3 July 2018

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3 July 2018

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3 July 2018

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3 July 2018

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3 July 2018

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Simvastatin for cognitive deficits and behavioural problems in patients with neurofibromatosis type 1 (NF1-SIMCODA): a randomised, placebo-controlled trial

3 July 2018

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Lovastatin improves impaired synaptic plasticity and phasic alertness in patients with neurofibromatosis type 1.

3 July 2018

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Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature

3 July 2018

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Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

3 July 2018

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Alterations in white matter microstructure in neurofibromatosis-1.

3 July 2018

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Lovastatin regulates brain spontaneous low-frequency brain activity in neurofibromatosis type 1.

3 July 2018

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Lovastatin as treatment for neurocognitive deficits in neurofibromatosis type 1: phase I study

3 July 2018

1 reference

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Altered white matter integrity and development in children with autism: a combined voxel-based morphometry and diffusion imaging study.

3 July 2018

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Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death

3 July 2018

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Neurofibromin regulation of ERK signaling modulates GABA release and learning

3 July 2018

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3 July 2018

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Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: a randomized controlled trial

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

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3 July 2018

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The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1

3 July 2018

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3 July 2018

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Pleiotropic effects of statins

3 July 2018

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3 July 2018

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3 July 2018

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Cerebral glucose metabolism in neurofibromatosis type 1 assessed with [18F]-2-fluoro-2-deoxy-D-glucose and PET.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

A Proton Magnetic Resonance Spectroscopic Study in Autism Spectrum Disorder Using a 3-Tesla Clinical Magnetic Resonance Imaging (MRI) System: The Anterior Cingulate Cortex and the Left Cerebellum.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Increasing the power of the Mann-Whitney test in randomized experiments through flexible covariate adjustment

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Prevalence of Autism Spectrum Disorder symptoms in children with neurofibromatosis type 1.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Neurofibromatosis type 1 and autism spectrum disorder

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Reduced cerebral arterial spin-labeled perfusion in children with neurofibromatosis type 1.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

GABA deficit in the visual cortex of patients with neurofibromatosis type 1: genotype-phenotype correlations and functional impact

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Autism and other psychiatric comorbidity in neurofibromatosis type 1: evidence from a population-based study

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Reduced thalamic 18F-flurodeoxyglucose retention in adults with neurofibromatosis type 1.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Accelerated maturation of white matter in young children with autism: a high b value DWI study.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Head circumference and height in autism: a study by the Collaborative Program of Excellence in Autism.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Model-free arterial spin labeling quantification approach for perfusion MRI.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

The relative sensitivity of the Clinical Global Impressions Scale and the Brief Psychiatric Rating Scale in antipsychotic drug trials.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Parent-defined target symptoms respond to risperidone in RUPP autism study: customer approach to clinical trials

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Treatment of ADHD in neurofibromatosis type 1.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Positron emission tomography in children with neurofibromatosis-1.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5824534

Neurofibromatosis. Conference statement. National Institutes of Health Consensus Development Conference

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29484149

12 December 2020

inferred from PubMed ID database lookup

The revised Conners' Parent Rating Scale (CPRS-R): factor structure, reliability, and criterion validity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29484149

12 December 2020

inferred from PubMed ID database lookup

Effects of cholesterol and simvastatin treatment in patients with Smith-Lemli-Opitz syndrome (SLOS)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29484149

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/S13229-018-0190-Z

1 reference

30 June 2018

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13229-018-0190-z

PMCID

5824534

1 reference

30 June 2018

PubMed ID

29484149

1 reference

30 June 2018