CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity. (Q49959398)

http://europepmc.org/abstract/MED/29449511

23 February 2018

title

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity. (English)

1 reference

http://europepmc.org/abstract/MED/29449511

23 February 2018

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

Maria Da Costa

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

Xinran Tian

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

Joel M Palefsky

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

Jennifer Doudna

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

author name string

Enbo Ma

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

Lucas B Harrington

3

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15 May 2020

language of work or name

English

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publication date

15 February 2018

1 reference

http://europepmc.org/abstract/MED/29449511

23 February 2018

published in

Science

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

volume

360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

page(s)

436-439

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15 May 2020

issue

6387

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Prevalence and risk factors for human papillomavirus infection of the anal canal in human immunodeficiency virus (HIV)-positive and HIV-negative homosexual men.

15 May 2020

cites work

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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

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CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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Structural basis of transcription initiation

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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

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Genome editing. The new frontier of genome engineering with CRISPR-Cas9

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Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity

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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

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DNase H Activity of Neisseria meningitidis Cas9.

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Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes

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Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.

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Bipartite recognition of target RNAs activates DNA cleavage by the Type III-B CRISPR-Cas system

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The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.

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The crystal structure of Cpf1 in complex with CRISPR RNA

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Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA

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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

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Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells.

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Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells.

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Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition

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Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

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Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array

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In vivo high-throughput profiling of CRISPR-Cpf1 activity

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Diversity and evolution of class 2 CRISPR-Cas systems

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A CRISPR-Cpf1 system for efficient genome editing and transcriptional repression in plants.

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Nucleic acid detection with CRISPR-Cas13a/C2c2

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Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.

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Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.

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A decade of discovery: CRISPR functions and applications

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Diversity, classification and evolution of CRISPR-Cas systems

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The Role of Replication-Associated Repair Factors on R-Loops

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Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors.

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12 December 2020

Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)

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Application of the Theory of Diffusion-controlled Reactions to Enzyme Kinetics

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAR6245

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAR6245

Polymerase chain reaction detection of human papillomavirus: quantitation may improve clinical utility

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAR6245

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

1 reference

13 October 2023

https://opencitations.net/index/coci/api/v1/citations/10.7554/ELIFE.55143

Identifiers

DOI

10.1126/SCIENCE.AAR6245

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6628903&resulttype=core&format=json

15 May 2020

1 reference