Recent Advances in CNS P2X7 Physiology and Pharmacology: Focus on Neuropsychiatric Disorders. (Q49957153)

23 February 2018

title

Recent Advances in CNS P2X7 Physiology and Pharmacology: Focus on Neuropsychiatric Disorders. (English)

1 reference

23 February 2018

1 reference

Anindya Bhattacharya

1

1 reference

23 February 2018

publication date

1 February 2018

1 reference

23 February 2018

Frontiers in Pharmacology

published in

1 reference

23 February 2018

volume

9

1 reference

23 February 2018

page(s)

30

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23 February 2018

Creative Commons Attribution 4.0 International

copyright license

start time

1 February 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Ketamine Alleviates Depressive-Like Behaviors via Down-Regulating Inflammatory Cytokines Induced by Chronic Restraint Stress in Mice.

14 August 2018

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4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.

14 August 2018

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14 August 2018

1 reference

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Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor.

14 August 2018

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A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334.

14 August 2018

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Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.

14 August 2018

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Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [¹¹C]A-740003 as a novel tracer of neuroinflammation.

14 August 2018

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Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms.

14 August 2018

1 reference

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Cognitive manic symptoms associated with the P2RX7 gene in bipolar disorder.

14 August 2018

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P2RX7 gene is associated consistently with mood disorders and predicts clinical outcome in three clinical cohorts.

14 August 2018

1 reference

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Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor

14 August 2018

1 reference

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Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor

14 August 2018

1 reference

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Discovery of 2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist

14 August 2018

1 reference

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Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5799703

Interleukin-1beta serum levels is increased in antidepressant-free elderly depressed patients.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5799703

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5799703

Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5799703

P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5799703

Clinical evaluation of the efficacy of the P2X7purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5799703

Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29449810

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Symptoms of postpartum depression associated with elevated levels of interleukin-1 beta during the first month postpartum

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29449810

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FPHAR.2018.00030

1 reference

23 February 2018

PMCID

5799703

1 reference

23 February 2018

PubMed ID

29449810

1 reference

23 February 2018