Human apolipoprotein E4 accelerates beta-amyloid deposition in APPsw transgenic mouse brain. (Q48744526)

15 February 2018

title

Human apolipoprotein E4 accelerates beta-amyloid deposition in APPsw transgenic mouse brain. (English)

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15 February 2018

author name string

Carter DB

1

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Dunn E

2

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McKinley DD

3

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Stratman NC

4

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Boyle TP

5

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Kuiper SL

6

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Oostveen JA

7

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Weaver RJ

8

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Boller JA

9

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Gurney ME

10

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publication date

1 October 2001

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15 February 2018

published in

Annals of Neurology

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volume

50

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page(s)

468-475

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issue

4

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Alzheimer diseases: a model of gene mutations and susceptibility polymorphisms for complex psychiatric diseases

cites work

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Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

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APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease.

21 January 2018

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Apolipoprotein E and Alzheimer disease

21 January 2018

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

21 January 2018

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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

1 reference

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

21 January 2018

1 reference

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

1 reference

Discovery of a brain promoter from the human transferrin gene and its utilization for development of transgenic mice that express human apolipoprotein E alleles

21 January 2018

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Human APOE protein localized in brains of transgenic mice.

21 January 2018

1 reference

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

21 January 2018

1 reference

The effects of age, apolipoprotein E phenotype and gender on the concentration of amyloid-beta (A beta) 40, A beta 4242, apolipoprotein E and transthyretin in human cerebrospinal fluid.

21 January 2018

1 reference

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

1 reference

Abeta-peptide length and apolipoprotein E genotype in Alzheimer's disease.

21 January 2018

1 reference

Apolipoprotein E genotype and deposits of Abeta40 and Abeta42 in Alzheimer disease.

21 January 2018

1 reference

Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease.

21 January 2018

1 reference

Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants.

21 January 2018

1 reference

Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease.

21 January 2018

1 reference

Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma

21 January 2018

1 reference

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

21 January 2018

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Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANA.1134

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15 February 2018

release_oarqj7va5rgjjnddvakaroyb4m

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/oarqj7va5rgjjnddvakaroyb4m

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

11601499

1 reference

15 February 2018