Helicobacter pylori CagA promotes Snail-mediated epithelial-mesenchymal transition by reducing GSK-3 activity. (Q48641425)

13 February 2018

title

Helicobacter pylori CagA promotes Snail-mediated epithelial-mesenchymal transition by reducing GSK-3 activity. (English)

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13 February 2018

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12

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13 February 2018

author name string

Da-Gyum Lee

1

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13 February 2018

Hyun Sil Kim

2

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13 February 2018

Yeo Song Lee

3

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13 February 2018

Shin Kim

4

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13 February 2018

So Young Cha

5

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13 February 2018

Ichiro Ota

6

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13 February 2018

Nam Hee Kim

7

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13 February 2018

Yong Hoon Cha

8

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13 February 2018

Dong Hyun Yang

9

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13 February 2018

Yoonmi Lee

10

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13 February 2018

Gyeong-Ju Park

11

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13 February 2018

Yong Chan Lee

13

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13 February 2018

language of work or name

English

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publication date

23 July 2014

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13 February 2018

published in

Nature Communications

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13 February 2018

volume

5

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13 February 2018

page(s)

4423

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13 February 2018

https://scigraph.springernature.com/pub.10.1038/ncomms5423

exact match

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cites work

Helicobacter pylori and gastrointestinal tract adenocarcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Coadaptation of Helicobacter pylori and humans: ancient history, modern implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Oncogenic mechanisms of the Helicobacter pylori CagA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

The versatility of Helicobacter pylori CagA effector protein functions: The master key hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

The basics of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

E-cadherin germline mutations in familial gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Identification of the Axin and Frat binding region of glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

MiRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Helicobacter pylori stimulates epithelial cell migration via CagA-mediated perturbation of host cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Cancer development induced by graded expression of Snail in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

The snail superfamily of zinc-finger transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Coordination between RAB GTPase and phosphoinositide regulation and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Role of CK1 in GSK3beta-mediated phosphorylation and degradation of snail.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

GSK-3: Functional Insights from Cell Biology and Animal Models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Inhibition of AMPK catabolic action by GSK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

A causal role for E-cadherin in the transition from adenoma to carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Deregulation of beta-catenin signal by Helicobacter pylori CagA requires the CagA-multimerization sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

GSK-3beta directly phosphorylates and activates MARK2/PAR-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

p53 regulates nuclear GSK-3 levels through miR-34-mediated Axin2 suppression in colorectal cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Kaposi's sarcoma-associated herpesvirus LANA protein downregulates nuclear glycogen synthase kinase 3 activity and consequently blocks differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

inferred from DOI database lookup

7 January 2021

based on heuristic

Wnt-dependent regulation of the E-cadherin repressor snail

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5423

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS5423

1 reference

13 February 2018

0 references

1 reference

13 February 2018