A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use. (Q48470797)

11 February 2018

title

A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use. (English)

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11 February 2018

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G Di Chiara

1

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11 February 2018

language of work or name

English

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publication date

1 January 1998

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11 February 2018

Journal of Psychopharmacology

published in

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11 February 2018

volume

12

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11 February 2018

page(s)

54-67

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11 February 2018

issue

1

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11 February 2018

Depression of mesolimbic dopamine transmission and sensitization to morphine during opiate abstinence

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SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade?

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Profound depression of mesolimbic dopamine release after morphine withdrawal in dependent rats

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Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat.

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21 January 2018

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The acquisition of responding with conditioned reinforcement: effects of cocaine, (+)-amphetamine and pipradrol

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Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats.

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Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals

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Cocaine withdrawal produces behavioral disruptions in rats.

21 January 2018

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Differences in dopamine clearance and diffusion in rat striatum and nucleus accumbens following systemic cocaine administration.

21 January 2018

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21 January 2018

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Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: electrophysiological and biochemical evidence

21 January 2018

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In-vivo brain dialysis of neurotransmitters

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The role of dopamine in drug abuse viewed from the perspective of its role in motivation.

21 January 2018

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Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats

21 January 2018

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Neurobiology of opiate abuse

21 January 2018

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On the preferential release of dopamine in the nucleus accumbens by amphetamine: further evidence obtained by vertically implanted concentric dialysis probes.

21 January 2018

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Modulatory functions of neurotransmitters in the striatum: ACh/dopamine/NMDA interactions

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Ethanol as a neurochemical surrogate of conventional reinforcers: the dopamine-opioid link.

21 January 2018

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Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area.

21 January 2018

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Cortical dopaminergic involvement in cocaine reinforcement.

21 January 2018

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Neuropharmacological assessment of cocaine self-administration into the medial prefrontal cortex.

21 January 2018

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Effects of pimozide on lever pressing behavior maintained on an intermittent reinforcement schedule.

21 January 2018

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Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis

21 January 2018

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Feeding and hypothalamic stimulation increase dopamine turnover in the accumbens

21 January 2018

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Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats.

21 January 2018

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Scheduled feeding caused activation of dopamine metabolism in the striatum of rats

21 January 2018

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Voltammetry in brain tissue--a new neurophysiological measurement

21 January 2018

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Postcocaine depression and sensitization of brain-stimulation reward: analysis of reinforcement and performance effects.

21 January 2018

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Amphetamine withdrawal: a behavioral evaluation

21 January 2018

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Neural mechanisms of drug reinforcement

21 January 2018

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A conditioned stimulus decreases extracellular dopamine in the nucleus accumbens after the development of a learned taste aversion

21 January 2018

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Sensory Neglect Produced by Lateral Hypothalamic Damage

21 January 2018

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Mesencephalic dopaminergic unit activity in the behaviorally conditioned rat.

21 January 2018

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Facilitation of sexual behaviors in the male rat associated with intra-VTA injections of opiates

21 January 2018

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Differential effect of cocaine on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens: comparison to amphetamine

21 January 2018

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Classical conditioning in drug-dependent humans

21 January 2018

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Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens

21 January 2018

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Decreased resistance to extinction after haloperidol: Implications for the role of dopamine in reinforcement

21 January 2018

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Suppression or facilitation of operant behaviour by raclopride dependent on concentration of sucrose reward

21 January 2018

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Increased extracellular dopamine in the nucleus accumbens of the rat elicited by a conditional stimulus for food: an electrochemical study.

21 January 2018

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Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens

21 January 2018

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Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Correlation of dose-dependent effects of acute amphetamine administration on behavior and local cerebral metabolism in rats.

21 January 2018

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Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats.

21 January 2018

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Scheduled eating increases dopamine release in the nucleus accumbens of food-deprived rats as assessed with on-line brain dialysis

21 January 2018

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How permanent was Vietnam drug addiction?

21 January 2018

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Limbic-striatal interactions in reward-related processes

21 January 2018

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Self-administration of GBR 12909 on a fixed ratio and progressive ratio schedule in rats.

21 January 2018

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Atypical neuroleptics increase self-administration of cocaine: An evaluation of a behavioural screen for antipsychotic activity

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens.

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

The neural basis of drug craving: an incentive-sensitization theory of addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Complex motor and sensorimotor functions of striatal and accumbens dopamine: involvement in instrumental behavior processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Conditioned dopamine release: dependence upon N-methyl-D-aspartate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Supersensitivity to the reinforcing effects of cocaine following 6-hydroxydopamine lesions to the medial prefrontal cortex in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Changes in response rates and reinforcement thresholds for intracranial self-stimulation during morphine withdrawal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Activity of dopamine neurons in the behaving primate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

In vivo voltammetry: some methodological considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Single unit activity of dopaminergic neurons in freely moving cuts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Alternation behavior, spatial discrimination, and reversal disturbances following 6-hydroxydopamine lesions in the nucleus accumbens of the rat.

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Habituation: A model phenomenon for the study of neuronal substrates of behavior

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Naltrexone in the treatment of alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Scope and limitations of in vivo brain dialysis: a comparison of its application to various neurotransmitter systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Increase in dopamine release from the nucleus accumbens in response to feeding: a model to study interactions between drugs and naturally activated dopaminergic neurons in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

Dynamics of drug dependence. Implications of a conditioning theory for research and treatment.

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Neuroleptic-Induced "Anhedonia" in Rats: Pimozide Blocks Reward Quality of Food

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Eating and drinking cause increased dopamine release in the nucleus accumbens and ventral tegmental area in the rat: measurement by in vivo microdialysis.

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Increased dopamine release in vivo in nucleus accumbens and caudate nucleus of the rat during drinking: a microdialysis study

21 January 2018

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https://api.crossref.org/works/10.1177%2F026988119801200108

Latent inhibition of conditioned dopamine release in rat nucleus accumbens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F026988119801200108

10.1177/026988119801200108

21 January 2018

Identifiers

DOI

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PubMed ID

9584969

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11 February 2018