Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade. (Q48412696)

11 February 2018

title

Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade. (English)

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11 February 2018

author name string

Yupeng Wang

series ordinal

1

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11 February 2018

Bing Su

series ordinal

2

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11 February 2018

Zhengui Xia

series ordinal

3

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11 February 2018

language of work or name

English

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publication date

26 September 2006

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11 February 2018

Journal of Biological Chemistry

published in

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11 February 2018

volume

281

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11 February 2018

issue

47

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11 February 2018

page(s)

35965-35974

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11 February 2018

Components of a new human protein kinase signal transduction pathway

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Primary structure of BMK1: a new mammalian map kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Isolation of MEK5 and differential expression of alternatively spliced forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Neurotrophins use the Erk5 pathway to mediate a retrograde survival response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Activation of BMK1 via tyrosine 1062 in RET by GDNF and MEN2A mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Radial glia serve as neuronal progenitors in all regions of the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Knockout of ERK5 causes multiple defects in placental and embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Neuronal nitric-oxide synthase mutant (Ser-1412 --> Asp) demonstrates surprising connections between heme reduction, NO complex formation, and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

c-Jun N-terminal kinase (JNK) and JNK interacting protein response in rat brain after transient middle cerebral artery occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Mechanisms of neurotrophin receptor vesicular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Rab proteins as membrane organizers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

A molecular motor or a regulator? Dynamin's in a class of its own.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Transforming growth factor (TGF)-beta 1 internalization: modulation by ligand interaction with TGF-beta receptors types I and II and a mechanism that is distinct from clathrin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Trk receptors: roles in neuronal signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

WNK1 activates ERK5 by an MEKK2/3-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Regulation of TrkB receptor tyrosine kinase and its internalization by neuronal activity and Ca2+ influx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve growth factor receptor TrkA regulates receptor trafficking and Erk5 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

Involvement of the Rho/Rac family member RhoG in caveolar endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605503200

21 January 2018

Identifiers

DOI

10.1074/JBC.M605503200

1 reference

11 February 2018

PubMed ID

17003042

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11 February 2018