Suppression of microglial activation is neuroprotective in a mouse model of human retinitis pigmentosa. (Q48301393)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24920619%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Suppression of microglial activation is neuroprotective in a mouse model of human retinitis pigmentosa (English)

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20 March 2020

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1

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20 March 2020

Kwok-Fai So

4

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20 March 2020

Bin Lin

6

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20 March 2020

5

George L Tipoe

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20 March 2020

author name string

Jia Xiao

2

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20 March 2020

Ke Wang

3

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20 March 2020

language of work or name

English

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publication date

1 June 2014

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20 March 2020

published in

Journal of Neuroscience

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20 March 2020

volume

34

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20 March 2020

issue

24

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20 March 2020

page(s)

8139-8150

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A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

20 March 2020

cites work

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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

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Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

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Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene

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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

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Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration

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Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism

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Neuroprotection of photoreceptors by minocycline in light-induced retinal degeneration

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The promise of minocycline in neurology.

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Identification of sequential events and factors associated with microglial activation, migration, and cytotoxicity in retinal degeneration in rd mice

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Control of microglial neurotoxicity by the fractalkine receptor

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Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study

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Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid.

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Microglia activation in retinal degeneration

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Sustained elevation of intracellular cGMP causes oxidative stress triggering calpain-mediated apoptosis in photoreceptor degeneration

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CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

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Microglia: active sensor and versatile effector cells in the normal and pathologic brain

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Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury

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Speed, spatial, and temporal tuning of rod and cone vision in mouse

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Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

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Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration

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Remodeling of cone photoreceptor cells after rod degeneration in rd mice.

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The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research

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Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling

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Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration.

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Cerebrovascular cyclooxygenase-1 expression, regulation, and role in hypothalamic-pituitary-adrenal axis activation by inflammatory stimuli.

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Immune activation in brain aging and neurodegeneration: too much or too little?

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Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid

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Mechanisms underlying inflammation in neurodegeneration

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Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

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Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double-deficient mice via modulation of microglia

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Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy

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Cellular and 3D optical coherence tomography assessment during the initiation and progression of retinal degeneration in the Ccl2/Cx3cr1-deficient mouse

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Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model

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Early activation of microglia triggers long-lasting impairment of adult neurogenesis in the olfactory bulb.

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Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

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Clinical evidence of sustained chronic inflammatory reaction in retinitis pigmentosa

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12 December 2020

Laboratory evidence of sustained chronic inflammatory reaction in retinitis pigmentosa

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12 December 2020

Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation

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12 December 2020

Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal

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12 December 2020

Microglial ramification and redistribution concomitant with the attenuation of choroidal neovascularization by neuroprotectin D1.

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12 December 2020

Cyclooxygenase-1-dependent prostaglandins mediate susceptibility to systemic inflammation-induced acute cognitive dysfunction

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12 December 2020

Microglial cells invade the outer retina as photoreceptors degenerate in Royal College of Surgeons rats

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12 December 2020

Impairment of pupillary responses and optokinetic nystagmus in the mGluR6-deficient mouse

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12 December 2020

Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

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12 December 2020

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

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12 December 2020

10.1523/JNEUROSCI.5200-13.2014

Identifiers

DOI

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20 March 2020

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20 March 2020

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