Elevated level of 8-hydroxydeoxyguanosine in DNA of liver, kidneys, and brain of Long-Evans Cinnamon rats. (Q48296681)

13 June 2018

title

Elevated level of 8-hydroxydeoxyguanosine in DNA of liver, kidneys, and brain of Long-Evans Cinnamon rats. (English)

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13 June 2018

author name string

F Yamamoto

1

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13 June 2018

H Kasai

2

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13 June 2018

Y Togashi

3

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13 June 2018

N Takeichi

4

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13 June 2018

T Hori

5

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13 June 2018

S Nishimura

6

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13 June 2018

publication date

1 May 1993

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13 June 2018

number of pages

4

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Japanese Journal of Cancer Research

inferred from page(s)

published in

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13 June 2018

volume

84

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13 June 2018

issue

5

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13 June 2018

page(s)

508-511

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13 June 2018

New mutation causing hereditary hepatitis in the laboratory rat.

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Free-radical generation by copper ions and hydrogen peroxide. Stimulation by Hepes buffer

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Metabolic predisposition of a novel mutant (LEC rats) to hereditary hepatitis and hepatoma: alterations of the drug metabolizing enzymes.

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Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

14 June 2018

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Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome.

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High sensitivity of the LEC rat liver to the carcinogenic effect of diethylnitrosamine.

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8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity

14 June 2018

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Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli

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Spontaneous hepatic copper accumulation in Long-Evans Cinnamon rats with hereditary hepatitis. A model of Wilson's disease

14 June 2018

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

14 June 2018

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An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA.

14 June 2018

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Abnormal copper accumulation in non-cancerous and cancerous liver tissues of LEC rats developing hereditary hepatitis and spontaneous hepatoma.

14 June 2018

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Assays for 8-hydroxy-2′-deoxyguanosine: A biomarker of in vivo oxidative DNA damage

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MutM, a protein that prevents G C→T A transversions, is formamidopyrimidine-DNA glycosylase

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Ubiquitous presence in mammalian cells of enzymatic activity specifically cleaving 8-hydroxyguanine-containing DNA

14 June 2018

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Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA

14 June 2018

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MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

14 June 2018

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High susceptibility to hepatocellular carcinoma development in LEC rats with hereditary hepatitis.

14 June 2018

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Spontaneous hepatitis in Long-Evans rats. A potential animal model for fulminant hepatitis in man

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12 December 2020

Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals in the presence of copper salts: A physiologically significant reaction?

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12 December 2020

Hydroxyl free radical is not the main active species in site-specific DNA damage induced by copper (II) ion and hydrogen peroxide

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12 December 2020

Copper and copper-binding protein in liver tumors

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12 December 2020

Copper-metallothionein induction in the liver of LEC rats

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12 December 2020

Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation

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12 December 2020

Diagnostic and prognostic value of serum copper and plasma fibrinogen in hepatic carcinoma

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12 December 2020

An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA+

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12 December 2020

10.1111/J.1349-7006.1993.TB00168.X

Identifiers

DOI

1 reference

13 June 2018

PMCID

5919176

1 reference

13 June 2018

PubMed ID

8320167

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13 June 2018