Aberrant promoter methylation of multiple genes in oligodendrogliomas and ependymomas. (Q48258599)

10 February 2018

title

Aberrant promoter methylation of multiple genes in oligodendrogliomas and ependymomas. (English)

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10 February 2018

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M Eva Alonso

1

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10 February 2018

M Josefa Bello

2

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10 February 2018

Pilar Gonzalez-Gomez

3

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10 February 2018

Dolores Arjona

4

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10 February 2018

Jesus Lomas

5

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10 February 2018

Jose M de Campos

6

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10 February 2018

Alberto Isla

7

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10 February 2018

Jose L Sarasa

8

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10 February 2018

Juan A Rey

9

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10 February 2018

publication date

1 July 2003

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10 February 2018

Cancer Genetics and Cytogenetics

published in

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10 February 2018

volume

144

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10 February 2018

issue

2

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10 February 2018

page(s)

134-142

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10 February 2018

Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas.

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Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.

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Analysis of the NF2 gene in oligodendrogliomas and ependymomas.

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Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas

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Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter-22q11.2.

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Identification of novel regions of allelic loss in ependymomas by high-resolution allelotyping with 384 microsatellite markers.

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Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

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Initiation of DNA replication at CpG islands in mammalian chromosomes

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Cancer epigenetics comes of age

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Concurrent inactivation of RB1 and TP53 pathways in anaplastic oligodendrogliomas.

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CDKN2A/p16 inactivation in the prognosis of oligodendrogliomas.

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Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumors.

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7 January 2021

Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas.

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Oligodendroglial tumors frequently demonstrate hypermethylation of the CDKN2A (MTS1, p16INK4a), p14ARF, and CDKN2B (MTS2, p15INK4b) tumor suppressor genes.

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7 January 2021

Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors

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Mutation analysis of the p73 gene in nonastrocytic brain tumours

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7 January 2021

hRAD54 gene and 1p high-resolution deletion-mapping analyses in oligodendrogliomas

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Loss of heterozygosity for distal markers on 22q in human gliomas

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NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas.

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Mutational analysis of p73 and p53 in human cancer cell lines.

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas--implications for tumor biology and potential clinical utility.

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7 January 2021

Infrequency of p53 gene mutations in ependymomas

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7 January 2021

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

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7 January 2021

Glutathione S-transferases: gene structure and regulation of expression

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Methylation and silencing of the Thrombospondin-1 promoter in human cancer.

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Transcriptional inactivation of TP73 expression in oligodendroglial tumors

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Changing views of the role of matrix metalloproteinases in metastasis

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7 January 2021

Methylation and colorectal cancer

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7 January 2021

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7 January 2021

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

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7 January 2021

CpG island methylation status and mutation analysis of the RB1 gene essential promoter region and protein-binding pocket domain in nervous system tumours

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7 January 2021

10.1016/S0165-4608(02)00928-7

Identifiers

DOI

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10 February 2018

PubMed ID

12850376

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10 February 2018