Structural Mechanisms of Gating in Ionotropic Glutamate Receptors. (Q48180487)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29037031%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

title

Structural Mechanisms of Gating in Ionotropic Glutamate Receptors (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29037031%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29037031%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

Alexander I Sobolevsky

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29037031%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

author name string

Alexander I Sobolevsky

series ordinal

2

1 reference

http://europepmc.org/abstract/PMC/5780838

9 February 2018

language of work or name

English

0 references

publication date

27 October 2017

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7 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29037031%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

volume

57

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7 April 2020

page(s)

267-276

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7 April 2020

issue

3

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Channel opening and gating mechanism in AMPA-subtype glutamate receptors

7 April 2020

cites work

1 reference

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Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes

22 May 2018

1 reference

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Role of the Ion Channel Extracellular Collar in AMPA Receptor Gating

22 May 2018

1 reference

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Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain

22 May 2018

1 reference

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Ionotropic AMPA-type glutamate and metabotropic GABAB receptors: determining cellular physiology by proteomes

22 May 2018

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Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.

22 May 2018

1 reference

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Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology.

22 May 2018

1 reference

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Stargazin Modulation of AMPA Receptors.

22 May 2018

1 reference

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Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs

22 May 2018

1 reference

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Structural basis of kainate subtype glutamate receptor desensitization

22 May 2018

1 reference

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Structural basis for integration of GluD receptors within synaptic organizer complexes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM.

22 May 2018

1 reference

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Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

22 May 2018

1 reference

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Mechanism of NMDA Receptor Inhibition and Activation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

A Molecular Determinant of Subtype-Specific Desensitization in Ionotropic Glutamate Receptors.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

AMPA Receptors as Therapeutic Targets for Neurological Disorders

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

The Transmembrane Domain Mediates Tetramerization of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Auxiliary Subunit GSG1L Acts to Suppress Calcium-Permeable AMPA Receptor Function

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Modulation of non-NMDA receptor gating by auxiliary subunits

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

22 May 2018

Glutamate receptor pores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structure and gating of tetrameric glutamate receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structural mechanism of glutamate receptor activation and desensitization

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Auxiliary subunits: shepherding AMPA receptors to the plasma membrane.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structure and dynamics of AMPA receptor GluA2 in resting, pre-open, and desensitized states

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structure of an agonist-bound ionotropic glutamate receptor

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

NMDA receptor structures reveal subunit arrangement and pore architecture

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Crystal structure of a heterotetrameric NMDA receptor ion channel

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Mechanical coupling maintains the fidelity of NMDA receptor-mediated currents

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Kainate receptors in health and disease.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

NMDA receptors in nervous system diseases.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Modal gating of GluN1/GluN2D NMDA receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Contribution of the M1 transmembrane helix and pre-M1 region to positive allosteric modulation and gating of N-methyl-D-aspartate receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Atomistic mechanism for the activation and desensitization of an AMPA-subtype glutamate receptor

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

The expanding social network of ionotropic glutamate receptors: TARPs and other transmembrane auxiliary subunits

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Mechanisms of Modal Activation of GluA3 Receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

The hidden energetics of ligand binding and activation in a glutamate receptor

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Cations but not anions regulate the responsiveness of kainate receptors.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structural landscape of isolated agonist-binding domains from single AMPA receptors

22 May 2018

1 reference

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Glutamate receptor ion channels: structure, regulation, and function

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Gating modes in AMPA receptors.

22 May 2018

1 reference

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X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

22 May 2018

1 reference

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Mechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution

22 May 2018

1 reference

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Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating

22 May 2018

1 reference

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Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexes.

22 May 2018

1 reference

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Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

The relationship between agonist potency and AMPA receptor kinetics

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Molecular mechanism of AMPA receptor noncompetitive antagonism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Stargazin reduces desensitization and slows deactivation of the AMPA-type glutamate receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structure and gating of the glutamate receptor ion channel

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structural basis for partial agonist action at ionotropic glutamate receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Modal gating of NMDA receptors and the shape of their synaptic response.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

How AMPA receptor desensitization depends on receptor occupancy.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Mechanism of glutamate receptor desensitization

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Functional assembly of AMPA and kainate receptors is mediated by several discrete protein-protein interactions

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Ligand-gated ion channel interactions with cytoskeletal and signaling proteins

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

The tetrameric structure of a glutamate receptor channel

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Unraveling the modular design of glutamate-gated ion channels

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Glutamate activates multiple single channel conductances in hippocampal neurons.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

The dynamic AMPA receptor extracellular region: a platform for synaptic protein interactions.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Stargazin modulates AMPA receptor gating and trafficking by distinct domains

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Structure and different conformational states of native AMPA receptor complexes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780838

Concentration-dependent substate behavior of native AMPA receptors

14 August 2018

1 reference

12 December 2020

Block of native Ca(2+)-permeable AMPA receptors in rat brain by intracellular polyamines generates double rectification

1 reference

12 December 2020

Intracellular spermine confers rectification on rat calcium-permeable AMPA and kainate receptors

1 reference

12 December 2020

Spermine mediates inward rectification of Ca(2+)-permeable AMPA receptor channels

1 reference

12 December 2020

10.1021/ACS.BIOCHEM.7B00891

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29037031%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29037031%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1 reference