CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein. (Q48174947)

http://europepmc.org/abstract/MED/28251317

9 February 2018

title

CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein. (English)

1 reference

http://europepmc.org/abstract/MED/28251317

9 February 2018

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1 reference

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1

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14 June 2020

author name string

Yanting Zeng

2

1 reference

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14 June 2020

Hongzi Du

3

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14 June 2020

Mengmeng Gong

4

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14 June 2020

Jin Peng

5

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14 June 2020

Buxi Zhang

6

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14 June 2020

Ming Lei

7

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14 June 2020

Fang Zhao

8

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14 June 2020

Weihua Wang

9

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14 June 2020

Xiaowei Li

10

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14 June 2020

Jianqiao Liu

11

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14 June 2020

publication date

1 March 2017

1 reference

http://europepmc.org/abstract/MED/28251317

9 February 2018

published in

Molecular Genetics and Genomics

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14 June 2020

volume

292

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14 June 2020

issue

3

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14 June 2020

page(s)

525-533

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https://scigraph.springernature.com/pub.10.1007/s00438-017-1299-z

14 June 2020

exact match

0 references

cites work

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Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins

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Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse.

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Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing

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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

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RNA-guided genome editing in Drosophila with the purified Cas9 protein

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CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

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Heritable multiplex genetic engineering in rats using CRISPR/Cas9.

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RNA-guided human genome engineering via Cas9

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Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

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One-step generation of different immunodeficient mice with multiple gene modifications by CRISPR/Cas9 mediated genome engineering

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Detection of the most common G6PD gene mutations in Chinese using amplification refractory mutation system

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PubMed

https://pubmed.ncbi.nlm.nih.gov/28251317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural analysis of a beta-thalassemia gene found in Taiwan

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28251317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28251317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00438-017-1299-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28251317%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference