Ataxin 1 (Q4812916)

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mammalian protein found in Homo sapiens
  • ATXN1
  • alternative ataxin1
  • ataxin-1
  • spinocerebellar ataxia type 1 protein
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Language Label Description Also known as
English
Ataxin 1
mammalian protein found in Homo sapiens
  • ATXN1
  • alternative ataxin1
  • ataxin-1
  • spinocerebellar ataxia type 1 protein

Statements

molecular function
protein binding
determination method
IPI
13 references
retrieved
8 April 2019
stated in
The role of LANP and ataxin 1 in E4F-mediated transcriptional repression
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
p80 coilin, a coiled body-specific protein, interacts with ataxin-1, the SCA1 gene product
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
Development and application of a DNA microarray-based yeast two-hybrid system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
8 April 2019
stated in
Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
protein binding
determination method
IBA
IPI
14 references
retrieved
1 January 2018
stated in
The role of LANP and ataxin 1 in E4F-mediated transcriptional repression
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
p80 coilin, a coiled body-specific protein, interacts with ataxin-1, the SCA1 gene product
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Development and application of a DNA microarray-based yeast two-hybrid system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IBA
identical protein binding
determination method
IBA
IPI
6 references
retrieved
1 January 2018
stated in
The AXH domain adopts alternative folds the solution structure of HBP1 AXH.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IPI
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IBA
cell component
nucleus
determination method
IBA
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IEA
retrieved
8 April 2019
stated in
Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals
GOA
curator
UniProt
UniProt protein ID
P54253
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IDA
retrieved
8 April 2019
stated in
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IDA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IDA
retrieved
8 April 2019
stated in
The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253
determination method
IBA
biological process
Gene Atlas image
PBB GE ATXN1 203232 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

 
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