The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors. (Q48125278)

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scientific article published on 27 June 2007

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English	The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors.	scientific article published on 27 June 2007

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1 January 2020

The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors (English)

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1 January 2020

Parkinson's disease

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John D. Salamone

5

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1 January 2020

Peter J McLaughlin

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1 January 2020

author name string

Adrienne J Betz

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Melissa Burgos

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Suzanne M Weber

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27 June 2007

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Psychopharmacology

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194

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3

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1 January 2020

347-359

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1 January 2020

https://scigraph.springernature.com/pub.10.1007/s00213-007-0844-6

0 references

Cholinergic-anticholinergic antagonism in parkinsonism.

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21 January 2018

Effects of chlordiazepoxide and scopolamine, but not aging, on the detection and identification of conditional visual stimuli.

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21 January 2018

Ropinirole for the treatment of tremor in early Parkinson's disease

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Molecular biology of muscarinic acetylcholine receptors

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DA agonists -- ergot derivatives: pergolide: management of Parkinson's disease

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International guide to drugs for Parkinson's disease

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Animal models of tremor.

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Comparative effects of cholinergic drugs and lesions of nucleus basalis or fimbria-fornix on delayed matching in rats

1 reference

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A randomly assigned double-blind cross-over study examining the relative anti-parkinsonian tremor effects of pramipexole and pergolide

1 reference

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12 December 2020

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Tardive dyskinesia treated with pimozide

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12 December 2020

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Anticholinergics for symptomatic management of Parkinson's disease

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12 December 2020

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Behavioral vigilance in rats: task validation and effects of age, amphetamine, and benzodiazepine receptor ligands.

1 reference

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The novel cannabinoid agonist AM 411 produces a biphasic effect on accuracy in a visual target detection task in rats

1 reference

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12 December 2020

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Pharmacological characterisation of spontaneous or drug-associated purposeless chewing movements in rats

1 reference

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12 December 2020

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Muscarinic acetylcholine receptors: signal transduction through multiple effectors.

1 reference

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12 December 2020

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Involvement of basal ganglia transmitter systems in movement initiation

1 reference

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12 December 2020

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Cholinergic stimulation of the ventrolateral striatum elicits mouth movements in rats: pharmacological and regional specificity

1 reference

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12 December 2020

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Dopamine agonists suppress cholinomimetic-induced tremulous jaw movements in an animal model of Parkinsonism: tremorolytic effects of pergolide, ropinirole and CY 208-243.

1 reference

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12 December 2020

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M3 muscarinic receptor activation of a delayed rectifier potassium current in canine atrial myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Tremulous jaw movements in rats: a model of parkinsonian tremor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

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The management of tremor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

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Severe parkinsonian symptom development on combination treatment with tacrine and haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

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Behavioural and pharmacological characterization of the mouth movements induced by muscarinic agonists in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

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Rationale for current therapies in Parkinson’s disease

1 reference

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12 December 2020

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Expression of muscarinic acetylcholine receptors (M1-, M2-, M3- and M4-type) in the neuromuscular junction of the newborn and adult rat.

1 reference

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12 December 2020

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Validation of the tremulous jaw movement model for assessment of the motor effects of typical and atypical antipychotics: effects of pimozide (Orap) in rats

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Effects of subchronic administration of clozapine, thioridazine and haloperidol on tests related to extrapyramidal motor function in the rat.

1 reference

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12 December 2020

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Effects of acute haloperidol and reserpine administration on vacuous jaw movements in three different age groups of rats

1 reference

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12 December 2020

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Vacuous jaw movements in rats induced by acute reserpine administration: interactions with different doses of apomorphine

1 reference

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Modelling working and reference memory in rats: effects of scopolamine on delayed matching-to-position(1,2).

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12 December 2020

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Interactions between dopamine D1 receptors and gamma-aminobutyric acid mechanisms in substantia nigra pars reticulata of the rat: neurochemical and behavioral studies

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Differential effect of systemic administration of bromocriptine and L-dopa on the release of acetylcholine from striatum of intact and 6-OHDA-treated rats.

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Motor behavioural changes after intracerebroventricular injection of 6-hydroxydopamine in the rat: an animal model of Parkinson's disease

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12 December 2020

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Tremulous jaw movements produced by acute tacrine administration: possible relation to parkinsonian side effects

1 reference

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12 December 2020

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The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism.

1 reference

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Pimozide in the treatment of newly admitted schizophrenic patients

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12 December 2020

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Parkinsonism onset in a patient concurrently using tiapride and donepezil

1 reference

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12 December 2020

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Double-blind, single-dose, cross-over study of the effects of pramipexole, pergolide, and placebo on rest tremor and UPDRS part III in Parkinson's disease

1 reference

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12 December 2020

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Rigidity decreases resting tremor intensity in Parkinson's disease: A [(123)I]beta-CIT SPECT study in early, nonmedicated patients

1 reference

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12 December 2020

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Relationship between animal models and clinical parkinsonism

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12 December 2020

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Brain implantations of engineered GABA-releasing cells suppress tremor in an animal model of Parkinsonism

1 reference

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12 December 2020

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Tacrine: a pharmacological approach to Alzheimer's disease.

1 reference

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12 December 2020

based on heuristic

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DA agonists -- non-ergot derivatives: ropinirole: management of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiparkinsonian drugs in the treatment of neuroleptic-induced extrapyramidal symptoms

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tremulous characteristics of the vacuous jaw movements induced by pilocarpine and ventrolateral striatal dopamine depletions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Motor dysfunction produced by tacrine administration in rats

1 reference

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12 December 2020

based on heuristic

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Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications

1 reference

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12 December 2020

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Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats

1 reference

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12 December 2020

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Donepezil for treatment of dementia with Lewy bodies: a case series of nine patients

1 reference

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12 December 2020

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Pimozide for schizophrenia or related psychoses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Neostriatal muscarinic receptor subtypes involved in the generation of tremulous jaw movements in rodents implications for cholinergic involvement in parkinsonism.

1 reference

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12 December 2020

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Spatial signal detection in rats is differentially disrupted by delta-9-tetrahydrocannabinol, scopolamine, and MK-801.

1 reference

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12 December 2020

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Contrasting effects of vasopressin, desglycinamide-vasopressin and amphetamine on a delayed matching to position task in rats.

1 reference

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12 December 2020

based on heuristic

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Effects of clozapine, thioridazine, risperidone and haloperidol on behavioral tests related to extrapyramidal motor function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias

1 reference

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12 December 2020

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1 reference

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12 December 2020

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Biotinylated m4-toxin demonstrates more M4 muscarinic receptor protein on direct than indirect striatal projection neurons.

1 reference

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12 December 2020

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Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions

1 reference

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12 December 2020

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Effects of acute and repeated clozapine injections on cholinomimetic-induced vacuous jaw movements

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of muscarinic facilitation of epileptiform discharges in immature rat neocortex

1 reference

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12 December 2020

based on heuristic

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Blockade of adenosine A2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on specific striatal regions

1 reference

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12 December 2020

based on heuristic

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Involvement of pallidal and nigral GABA mechanisms in the generation of tremulous jaw movements in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tremulous jaw movements induced by the acetylcholinesterase inhibitor tacrine: effects of antiparkinsonian drugs

1 reference

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12 December 2020

based on heuristic

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Attenuation of Stimulus Sensitivity induced by Scopolamine

1 reference

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12 December 2020

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Pathophysiology of the basal ganglia in Parkinson's disease.

1 reference

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12 December 2020

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Binding of selective antagonists to four muscarinic receptors (M1 to M4) in rat forebrain

1 reference

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12 December 2020

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Vacuous jaw movements and feeding deficits in rats with ventrolateral striatal dopamine depletion: possible relation to parkinsonian symptoms.

1 reference

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12 December 2020

based on heuristic

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Behavioral and electromyographic characterization of the local frequency of tacrine-induced tremulous jaw movements

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathophysiology of tremor

1 reference

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12 December 2020

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Effects of H1 antagonists on cholinomimetic-induced tremulous jaw movements: studies of diphenhydramine, doxepin, and mepyramine.

1 reference

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12 December 2020

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Effects of anticholinergic drugs selective for muscarinic receptor subtypes on prepulse inhibition in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Parkinsonian syndrome related to tacrine]

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lateral striatal cholinergic mechanisms involved in oral motor activities in the rat.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinsonism induced by pyridostigmine

1 reference

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12 December 2020

based on heuristic

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Blockade of spatial learning by the M1 muscarinic antagonist pirenzepine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacological characterisation of pilocarpine-induced purposeless chewing behaviour in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of Parkinson's disease: from clinical neurology to basic neuroscience and back

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electromyographic differentiation of tremors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Potentiation of sympathetic neuromuscular transmission mediated by muscarinic receptors in guinea pig isolated vas deferens

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic manipulation of perioral behaviour induced by chronic neuroleptic administration to rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated scopolamine injections sensitize rats to pilocarpine-induced vacuous jaw movements and enhance striatal muscarinic receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vacuous jaw movements induced by acute reserpine and low-dose apomorphine: possible model of parkinsonian tremor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of binding parameters of [3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of selective antagonism or depletion of the cholinergic system on visual discrimination performance in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexistence of Parkinson's disease and myasthenia gravis: a case report.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exacerbation of parkinsonism by tacrine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary Report: Intracranial Cholinergic Drug Infusion in Patients with Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Systemic absorption and anticholinergic activity of topically applied tropicamide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of neurological deficits: how relevant is the rat?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Primate models of movement disorders of basal ganglia origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Therapeutic opportunities for muscarinic receptors in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible association between donepezil and worsening Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of newer antipsychotics on extrapyramidal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

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Loss of anti-cataleptic effect of scopolamine in mice lacking muscarinic acetylcholine receptor subtype 4

1 reference

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12 December 2020

based on heuristic

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1 reference

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12 December 2020

based on heuristic

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The clinical use of anticholinergic drugs as treatment for extrapyramidal side effects of neuroleptic drugs

1 reference

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12 December 2020

based on heuristic

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Pramipexole in patients with Parkinson's disease and marked drug resistant tremor: a randomised, double blind, placebo controlled multicentre study

1 reference

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12 December 2020

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Antiparkinsonian and behavioral effects of inactivation of the substantia nigra pars reticulata in hemiparkinsonian primates

1 reference

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12 December 2020

based on heuristic

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Motor effects of GABA(A) antagonism in globus pallidus: studies of locomotion and tremulous jaw movements in rats

1 reference

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12 December 2020

based on heuristic

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Vacuous jaw movements induced by sub-chronic administration of haloperidol: interactions with scopolamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substantia nigra pars reticulata GABA is involved in the regulation of operant lever pressing: pharmacological and microdialysis studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD 102807, a novel muscarinic M4 receptor antagonist, discriminates between striatal and cortical muscarinic receptors coupled to cyclic AMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17594079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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