Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease. (Q48096368)

8 February 2018

title

Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease. (English)

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8 February 2018

main subject

cognitive dysfunction

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6

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8 February 2018

author name string

King DL

1

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8 February 2018

Arendash GW

2

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8 February 2018

Crawford F

3

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8 February 2018

Sterk T

4

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8 February 2018

Menendez J

5

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8 February 2018

language of work or name

English

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publication date

1 September 1999

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8 February 2018

Behavioural Brain Research

published in

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8 February 2018

volume

103

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8 February 2018

issue

2

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8 February 2018

page(s)

145-162

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8 February 2018

Selective improvement of aged rat short-term spatial memory by 3,4-diaminopyridine.

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

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A behavioural analysis of rats with damage to the medial prefrontal cortex using the Morris water maze: evidence for behavioural flexibility, but not for impaired spatial navigation.

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Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

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Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

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Differential effects of hippocampal lesions upon sequential tasks and maze learning by the rat

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Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

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Mice, gene targeting and behaviour: more than just genetic background

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Blind rats are not profoundly impaired in the reference memory Morris water maze and cannot be clearly discriminated from rats with cognitive deficits in the cued platform task.

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Lack of beta-amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations.

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

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Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.

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Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease.

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Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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7 January 2021

Transgenic mice for the amyloid precursor protein 695 isoform have impaired spatial memory

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7 January 2021

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Identifiers

DOI

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8 February 2018

PubMed ID

10513583

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8 February 2018