Aryl hydrocarbon receptor nuclear translocator (Q4802695)

http://www.ebi.ac.uk/interpro/protein/P27540

PAS domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27540

Helix-loop-helix DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27540

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

PAS fold family

1 reference

PAC motif domain, protein family

1 reference

PAS domain, protein family

1 reference

sequence-specific DNA binding

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

27 March 2018

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27540&geneProductId=UniProtKB:P27540

protein dimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

DNA-binding transcription factor activity

4 references

8 April 2019

Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

aryl hydrocarbon receptor binding

1 reference

8 April 2019

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

transcription factor binding

IPI

3 references

8 April 2019

Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

13 references

8 April 2019

Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Network organization of the human autophagy system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Allosteric inhibition of hypoxia inducible factor-2 with small molecules

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Artificial ligand binding within the HIF2 PAS-B domain of the HIF2 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

RKTG inhibits angiogenesis by suppressing MAPK-mediated autocrine VEGF signaling and is downregulated in clear-cell renal cell carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Cbx4 governs HIF-1α to potentiate angiogenesis of hepatocellular carcinoma by its SUMO E3 ligase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

IPI

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27540&geneProductId=UniProtKB:P27540

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27540&geneProductId=UniProtKB:P27540

5 June 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27540&geneProductId=UniProtKB:P27540

protein homodimerization activity

ISA

1 reference

8 April 2019

Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

protein heterodimerization activity

3 references

8 April 2019

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

DNA-binding transcription factor activity, RNA polymerase II-specific

5 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

transcription coactivator activity

1 reference

8 April 2019

Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

nuclear receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

6 references

8 April 2019

Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

8 April 2019

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of vascular endothelial growth factor receptor signaling pathway

biological process

1 reference

8 April 2019

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of endothelial cell proliferation

1 reference

8 April 2019

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

regulation of transcription from RNA polymerase II promoter in response to oxidative stress

1 reference

8 April 2019

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of erythrocyte differentiation

1 reference

8 April 2019

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

embryonic placenta development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

mRNA transcription by RNA polymerase II

1 reference

8 April 2019

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of protein sumoylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

intracellular receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

regulation of transcription from RNA polymerase II promoter in response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of vascular endothelial growth factor production

1 reference

8 April 2019

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of glycolytic process

1 reference

8 April 2019

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

positive regulation of hormone biosynthetic process

1 reference

8 April 2019

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

xenobiotic metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

transcription, DNA-templated

1 reference

8 April 2019

Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540

Gene Atlas image

PBB GE ARNT 218221 at fs.png
732 × 530; 12 KB

0 references

Identifiers

MeSH descriptor ID

D051784

subject named as

Aryl Hydrocarbon Receptor Nuclear Translocator

0 references

MeSH tree code

D12.776.157.530.750.100

0 references

D12.776.260.103.625.500

0 references

D12.776.543.585.750.100

0 references

D12.776.930.125.625.500

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016