Germline BRCA2 mutations and the risk of esophageal squamous cell carcinoma. (Q47870583)

6 February 2018

title

Germline BRCA2 mutations and the risk of esophageal squamous cell carcinoma. (English)

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6 February 2018

esophageal squamous cell carcinoma

main subject

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2

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Shahryar Semnani

13

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Steven A. Narod

17

object named as

Narod SA

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5

Islami F

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14

Boffetta P

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Akbari MR

1

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Nasrollahzadeh D

3

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Amanian D

4

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Li S

6

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Zandvakili I

7

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Shakeri R

8

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Sotoudeh M

9

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Aghcheli K

10

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Salahi R

11

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Pourshams A

12

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Dawsey SM

15

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Ghadirian P

16

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language of work or name

English

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publication date

27 August 2007

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6 February 2018

published in

Oncogene

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volume

27

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6 February 2018

page(s)

1290-1296

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issue

9

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6 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210739

exact match

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cites work

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Internal repeats in the BRCA2 protein sequence

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Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2

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Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

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BRCA2 associates with acetyltransferase activity when bound to P/CAF

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Familial history of esophageal cancer

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Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

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Biallelic inactivation of BRCA2 in Fanconi anemia

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EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

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Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1

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A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression

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Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer.

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Transcriptional activation functions in BRCA2

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RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

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Molecular pathogenesis of Fanconi anemia: recent progress

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BRCA2 suppresses cell proliferation via stabilizing MAGE-D1

21 January 2018

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7 January 2021

Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis

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7 January 2021

Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining

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7 January 2021

Common genetic variants of TP53 and BRCA2 in esophageal cancer patients and healthy individuals from low and high risk areas of northern China

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7 January 2021

Identification of novel regions of allelic loss from a genomewide scan of esophageal squamous-cell carcinoma in a high-risk Chinese population

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7 January 2021

Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer

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7 January 2021

Allelic loss on chromosome bands 13q11-q13 in esophageal squamous cell carcinoma

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7 January 2021

A polymorphic stop codon in BRCA2

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210739

1 reference

6 February 2018

PubMed ID

17724471

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6 February 2018