Preservation of mucosal and systemic adjuvant properties of ISCOMS in the absence of functional interleukin-4 or interferon-gamma. (Q47864940)

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13 November 2019

title

Preservation of mucosal and systemic adjuvant properties of ISCOMS in the absence of functional interleukin-4 or interferon-gamma (English)

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13 November 2019

4

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13 November 2019

author name string

R E Smith

series ordinal

1

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13 November 2019

A M Donachie

series ordinal

2

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13 November 2019

F H McLaren

series ordinal

3

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13 November 2019

publication date

1 April 1998

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13 November 2019

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13 November 2019

volume

93

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13 November 2019

issue

4

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13 November 2019

page(s)

556-562

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Induction of Th1 and Th2 CD4+ T cell responses by oral or parenteral immunization with ISCOMS

13 November 2019

cites work

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Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection

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Initiation of cytotoxic T-cell response and protection of Balb/c mice by vaccination with an experimental ISCOMs respiratory syncytial virus subunit vaccine

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The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice

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Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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Response to influenza infection in mice with a targeted disruption in the interferon gamma gene

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Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

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Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response

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The role of interleukin-6 in mucosal IgA antibody responses in vivo

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Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans

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Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

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A lavage technique allowing repeated measurement of IgA antibody in mouse intestinal secretions

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12 December 2020

Immune-stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunization with protein antigens.

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12 December 2020

IFN-gamma receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses

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12 December 2020

Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses

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12 December 2020

Immune responses and protective effect in mice vaccinated orally with surface sporozoite protein of Eimeria falciformis in ISCOMs

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12 December 2020

T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction

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12 December 2020

Induction of systemic and mucosal immune responses following immunization with somatostatin-avidin complexes incorporated into ISCOMS

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12 December 2020

Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location.

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12 December 2020

Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses

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12 December 2020

IL-6-deficient mice exhibit normal mucosal IgA responses to local immunizations and Helicobacter felis infection

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12 December 2020

Exacerbated viral hepatitis in IFN-gamma receptor-deficient mice is not suppressed by IL-12.

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12 December 2020

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

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12 December 2020

Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route

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12 December 2020

Vaccination of class I major histocompatibility complex (MHC)-restricted murine CD8+ cytotoxic T lymphocytes towards soluble antigens: immunostimulating-ovalbumin complexes enter the class I MHC-restricted antigen pathway and allow sensitization aga

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12 December 2020

Effects of interferon-gamma and tumour necrosis factor-alpha on the development of cytotoxic T lymphocytes in autologous mixed lymphocyte tumour cultures with human melanoma

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12 December 2020

IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis

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12 December 2020

The role of T-cell subsets and cytokines in the regulation of infection

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12 December 2020

Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones

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12 December 2020

Regulation by glutathione of interleukin-4 activity on cytotoxic T cells

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12 December 2020

Generation of rat Th2-like cells in vitro is interleukin-4-dependent and inhibited by interferon-gamma

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12 December 2020

Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression.

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12 December 2020

The role of IL-5 in IgA B cell differentiation

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12 December 2020

10.1046/J.1365-2567.1998.00469.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9659229%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

PMC publication ID

1364135

0 references

1 reference