Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment. (Q47851530)

6 February 2018

title

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment. (English)

1 reference

6 February 2018

0 references

1 reference

cognitive dysfunction

1 reference

Candice E Van Skike

1

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author name string

Jordan B Jahrling

2

1 reference

6 February 2018

Angela B Olson

3

1 reference

6 February 2018

Naomi L Sayre

4

1 reference

6 February 2018

Stacy A Hussong

5

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6 February 2018

Zoltan I Ungvari

6

1 reference

6 February 2018

James D Lechleiter

7

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6 February 2018

Veronica Galvan

8

1 reference

6 February 2018

publication date

22 December 2017

1 reference

6 February 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

1 reference

6 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5966773/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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Reduction of endothelial tight junction proteins is related to cerebral aneurysm formation in rats

26 August 2018

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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

26 August 2018

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Hemoglobin-induced oxidative stress contributes to matrix metalloproteinase activation and blood-brain barrier dysfunction in vivo

26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease

26 August 2018

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Activated mTOR and PKR kinases in lymphocytes correlate with memory and cognitive decline in Alzheimer's disease.

26 August 2018

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Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus

26 August 2018

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26 August 2018

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A simple method for isolation and characterization of mouse brain microvascular endothelial cells

26 August 2018

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Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier.

26 August 2018

1 reference

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Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin

26 August 2018

1 reference

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Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration

26 August 2018

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Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients.

26 August 2018

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Permeability of blood-brain barrier to various sized molecules.

26 August 2018

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Decreased junctional adhesion molecule-A expression during blood-brain barrier breakdown

26 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29351469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effect of ABCG1 deficiency on atherosclerotic lesion development in LDL receptor knockout mice depends on the stage of atherogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29351469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPHEART.00570.2017

1 reference

6 February 2018

0 references

1 reference

6 February 2018