Improved Determination of Drug Metabolism by Perifusion of Recombinant V79 Cells Carrying Human CYP3A4. (Q47851296)

6 February 2018

title

Improved Determination of Drug Metabolism by Perifusion of Recombinant V79 Cells Carrying Human CYP3A4. (English)

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6 February 2018

author name string

Gebhardt R

1

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6 February 2018

Lippert C

2

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6 February 2018

Schneider A

3

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6 February 2018

Doehmer J

4

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6 February 2018

publication date

1 August 1999

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6 February 2018

number of pages

5

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inferred from page(s)

published in

Toxicology in Vitro

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6 February 2018

volume

13

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6 February 2018

issue

4-5

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6 February 2018

page(s)

639-643

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6 February 2018

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

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The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and CYP2A3.

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A NIH/3T3 cell line stably expressing human cytochrome P450-3A4 used in combination with a lacZ' shuttle vector to study mutagenicity

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7 January 2021

V79 Chinese hamster cells genetically engineered for cytochrome P450 and their use in mutagenicity and metabolism studies

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Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.

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Genetically engineered mammalian cells and applications

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Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes

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7 January 2021

Perifusion Culture of Hepatocytes

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7 January 2021

Perifusion of co-cultured hepatocytes: optimization of studies on drug metabolism and cytotoxicity in vitro

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7 January 2021

Human cytochromes P450: problems and prospects

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Sensitive detection of growth stimulating tumour promoters in perifused primary rat hepatocyte cultures

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7 January 2021

Stable expression of human cytochrome P450 3A4 in V79 cells and its application for metabolic profiling of ergot derivatives

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Immortalized human hepatocytes as a tool for the study of hepatocytic (de-)differentiation

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Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells.

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7 January 2021

Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine

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7 January 2021

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

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Genetically engineered V79 Chinese hamster cells for stable expression of human cytochrome P450IA2

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7 January 2021

10.1016/S0887-2333(99)00020-X

Identifiers

DOI

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6 February 2018

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6 February 2018