Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region. (Q47723087)

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7 January 2020

title

Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region (English)

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7 January 2020

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5

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7 January 2020

author name string

Saito Y

1

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Sunamura M

2

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Motoi F

3

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Abe H

4

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Duda DG

6

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Hoshida T

7

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Fukuyama S

8

1 reference

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Hamada H

9

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Matsuno S

10

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publication date

1 March 2006

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7 January 2020

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volume

13

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issue

3

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page(s)

242-252

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https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700902

7 January 2020

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0 references

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

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Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

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Targeting tumors through the HIF system.

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Effective gene therapy for pancreatic cancer by cytokines mediated by restricted replication-competent adenovirus

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Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

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7 January 2021

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

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Reverse transcription-polymerase chain reaction products of alternatively spliced mRNAs form DNA heteroduplexes and heteroduplex complexes

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a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

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Gene therapy for intraperitoneally disseminated pancreatic cancers by Escherichia coli uracil phosphoribosiltransferase (UPRT) gene mediated by restricted replication-competent adenoviral vectors.

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