Sex-specific transcriptional signatures in human depression. (Q47641958)

4 February 2018

title

Sex-specific transcriptional signatures in human depression. (English)

1 reference

4 February 2018

author

Zachary Lorsch

11

1 reference

4 February 2018

Hope Kronman

Hope Kronman

16

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Caroline Ménard

Caroline Menard

4

0 references

Georgia E Hodes

Georgia E Hodes

14

0 references

Michael E Cahill

Michael Cahill

10

0 references

Gustavo Turecki

25

Gustavo Turecki

1 reference

4 February 2018

28

Eric J Nestler

1 reference

PubMed ID

28825715

4 February 2018

Erin Siciliano Calipari

13

Erin S Calipari

1 reference

4 February 2018

Benoit Labonté

Benoit Labonté

1

0 references

Yan Dong

Yan Dong

19

0 references

Rachael L. Neve

20

Rachael L Neve

1 reference

4 February 2018

Carol Tamminga

23

Carol Tamminga

1 reference

4 February 2018

Yong-Hwee Eddie Loh

9

Yong-Hwee E Loh

1 reference

4 February 2018

author name string

Olivia Engmann

2

1 reference

4 February 2018

Immanuel Purushothaman

3

1 reference

4 February 2018

Junshi Wang

5

1 reference

4 February 2018

Chunfeng Tan

6

1 reference

4 February 2018

Joseph R Scarpa

7

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4 February 2018

Gregory Moy

8

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4 February 2018

Peter J Hamilton

12

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4 February 2018

Orna Issler

15

1 reference

4 February 2018

Madeline Pfau

17

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4 February 2018

Aleksandar L J Obradovic

18

1 reference

4 February 2018

Scott Russo

21

1 reference

4 February 2018

Andrew Kazarskis

22

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4 February 2018

Naguib Mechawar

24

1 reference

4 February 2018

Bin Zhang

26

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4 February 2018

Li Shen

27

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4 February 2018

language of work or name

English

0 references

publication date

21 August 2017

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4 February 2018

published in

Nature Medicine

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4 February 2018

volume

23

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4 February 2018

page(s)

1102-1111

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4 February 2018

issue

9

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4 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5734943/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5734943

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nm.4386

0 references

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

29 September 2018

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29 September 2018

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29 September 2018

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Sex differences of gray matter morphology in cortico-limbic-striatal neural system in major depressive disorder

29 September 2018

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Synaptic plasticity in depression: molecular, cellular and functional correlates

29 September 2018

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29 September 2018

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Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder

29 September 2018

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29 September 2018

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Epigenetic mechanisms of depression and antidepressant action

29 September 2018

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Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide

29 September 2018

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Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

29 September 2018

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Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression

29 September 2018

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Neuron density and serotonin receptor binding in prefrontal cortex in suicide

29 September 2018

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A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism

29 September 2018

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Possible antidepressant effects and mechanisms of memantine in behaviors and synaptic plasticity of a depression rat model.

29 September 2018

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NMDA receptor blockade alters stress-induced dendritic remodeling in medial prefrontal cortex

29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

1 reference

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Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

29 September 2018

1 reference

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29 September 2018

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29 September 2018

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Gender differences in alpha-[(11)C]MTrp brain trapping, an index of serotonin synthesis, in medication-free individuals with major depressive disorder: a positron emission tomography study

29 September 2018

1 reference

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Association between repeated unpredictable chronic mild stress (UCMS) procedures with a high fat diet: a model of fluoxetine resistance in mice

29 September 2018

1 reference

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Gene expression studies in major depression.

29 September 2018

1 reference

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Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

29 September 2018

1 reference

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Chronic stress enhances synaptic plasticity due to disinhibition in the anterior cingulate cortex and induces hyper-locomotion in mice

29 September 2018

1 reference

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29 September 2018

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Transcriptional expression of serotonergic regulators in laser-captured microdissected dorsal raphe neurons of subjects with major depressive disorder: sex-specific differences

29 September 2018

1 reference

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Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1).

29 September 2018

1 reference

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Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression

29 September 2018

1 reference

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Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers

29 September 2018

1 reference

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Sex differences in hormonal responses to a social stressor in chronic major depression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Role of nuclear factor kappaB in ovarian hormone-mediated stress hypersensitivity in female mice.

29 September 2018

1 reference

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CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits

29 September 2018

1 reference

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29 September 2018

1 reference

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Functional organization of the transcriptome in human brain

29 September 2018

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Sex differences in response to citalopram: a STAR*D report

29 September 2018

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A history of corticosterone exposure regulates fear extinction and cortical NR2B, GluR2/3, and BDNF

29 September 2018

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Eigen-R2 for dissecting variation in high-dimensional studies

29 September 2018

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Geometric interpretation of gene coexpression network analysis

29 September 2018

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Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder.

29 September 2018

1 reference

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Emx and Nfi genes regulate cortical development and axon guidance in the telencephalon

29 September 2018

1 reference

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Protection of stress-induced impairment of hippocampal/prefrontal LTP through blockade of glucocorticoid receptors: implication of MEK signaling.

29 September 2018

1 reference

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Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances

29 September 2018

1 reference

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Gene expression profiling of major depression and suicide in the prefrontal cortex of postmortem brains

29 September 2018

1 reference

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Gene expression profiling in postmortem prefrontal cortex of major depressive disorder

29 September 2018

1 reference

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Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

29 September 2018

1 reference

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Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression.

29 September 2018

1 reference

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The varied clinical presentations of major depressive disorder

29 September 2018

1 reference

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Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Patterns of gene expression in the limbic system of suicides with and without major depression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Cortical trapping of alpha-[(11)C]methyl-l-tryptophan, an index of serotonin synthesis, is lower in females than males.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

29 September 2018

1 reference

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A general framework for weighted gene co-expression network analysis

29 September 2018

1 reference

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Risk factors for suicide completion in major depression: a case-control study of impulsive and aggressive behaviors in men.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

29 September 2018

1 reference

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Assessment of the dexamethasone/CRH test as a state-dependent marker for hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depressive episode: a Multicenter Study.

29 September 2018

1 reference

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Sex differences in antidepressant response in recent antidepressant clinical trials

29 September 2018

1 reference

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Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Deep brain stimulation for treatment-resistant depression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Hippocampal volume and depression: a meta-analysis of MRI studies

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Dysregulation of the fibroblast growth factor system in major depression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Bioconductor: open software development for computational biology and bioinformatics

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Puberty, ovarian steroids, and stress

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Anatomic evaluation of the orbitofrontal cortex in major depressive disorder

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Cortisol responses to daily events in major depressive disorder

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Gender differences in unipolar depression: an update of epidemiological findings and possible explanations

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Epidemiology of women and depression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Hippocampal changes in patients with a first episode of major depression.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Volumetric reduction in left subgenual prefrontal cortex in early onset depression.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Molecular mechanisms underlying cell fate specification in the developing telencephalon

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Gender differences in trauma and posttraumatic stress disorder.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

The validity of proxy-based data in suicide research: a study of patients 50 years of age and older who attempted suicide. II. Life events, social support and suicidal behavior

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Gender differences in the efficacy of fluoxetine and maprotiline in depressed patients: a double-blind trial of antidepressants with serotonergic or norepinephrinergic reuptake inhibition profile

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Gender differences in treatment response to sertraline versus imipramine in chronic depression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Gender differences in chronic major and double depression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

The psychological autopsy approach to studying suicide: a review of methodological issues

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Validity of DSM-III-R diagnosis by psychological autopsy: a comparison with clinician ante-mortem diagnosis.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Electrophysiological and morphological properties of layers V-VI principal pyramidal cells in rat prefrontal cortex in vitro.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Linkage disequilibrium analysis in young populations: pseudo-vitamin D-deficiency rickets and the founder effect in French Canadians

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Psychopathology and early experience: a reappraisal of retrospective reports

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Sex and depression in the National Comorbidity Survey. I: Lifetime prevalence, chronicity and recurrence

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Sex differences in sensitivity of the hypothalamic-pituitary-adrenal axis.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Age-associated changes of pituitary-adrenocortical hormone regulation in humans: importance of gender.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5734943

Systemic interferon-alpha regulates interferon-stimulated genes in the central nervous system.

29 September 2018

1 reference

The brain reward circuitry in mood disorders

21 January 2018

1 reference

Normalization of RNA-seq data using factor analysis of control genes or samples

21 January 2018

1 reference

affy--analysis of Affymetrix GeneChip data at the probe level

21 January 2018

1 reference

Is my network module preserved and reproducible?

21 January 2018

1 reference

Volumetric Analysis of the Prefrontal Cortex, Amygdala and Hippocampus in Major Depression

21 January 2018

1 reference

7 January 2021

Effect of chronic mild stress on hippocampal transcriptome in mice selected for high and low stress-induced analgesia and displaying different emotional behaviors

1 reference

7 January 2021

The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases

1 reference

7 January 2021

Risk factors for completed suicide in schizophrenia and other chronic psychotic disorders: A case–control study

1 reference

7 January 2021

The validity of diagnoses obtained through the psychological autopsy procedure in adolescent suicide victims: use of family history

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28825715

12 December 2020

inferred from PubMed ID database lookup

ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28825715

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NM.4386

1 reference

4 February 2018

0 references

1 reference

4 February 2018