Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse. (Q47435856)

16 January 2018

title

Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse. (English)

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16 January 2018

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9

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16 January 2018

T. J. Hamblin

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object named as

Terry Hamblin

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16 January 2018

Jane C Stinchcombe

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object named as

Jane C Stinchcombe

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16 January 2018

author name string

Richard H Clark

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16 January 2018

Anna Day

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16 January 2018

Emma Blott

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16 January 2018

Sarah Booth

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16 January 2018

Giovanna Bossi

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16 January 2018

E Graham Davies

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16 January 2018

language of work or name

English

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publication date

19 October 2003

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16 January 2018

published in

Nature Immunology

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16 January 2018

volume

4

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16 January 2018

page(s)

1111-1120

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16 January 2018

issue

11

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16 January 2018

Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

cites work

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The secretory synapse: the secrets of a serial killer

21 January 2018

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The immunological synapse of CTL contains a secretory domain and membrane bridges.

21 January 2018

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Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

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Rab27a is required for regulated secretion in cytotoxic T lymphocytes

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Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

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Analysis of the lysosomal storage disease Chediak-Higashi syndrome

21 January 2018

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Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor

21 January 2018

1 reference

Nonsense mutations in ADTB3A cause complete deficiency of the beta3A subunit of adaptor complex-3 and severe Hermansky-Pudlak syndrome type 2

21 January 2018

1 reference

Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells.

21 January 2018

1 reference

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.

21 January 2018

1 reference

AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes

21 January 2018

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Assembly and function of AP-3 complexes in cells expressing mutant subunits.

21 January 2018

1 reference

Characterization of the adaptor-related protein complex, AP-3

21 January 2018

1 reference

Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes

21 January 2018

1 reference

Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

21 January 2018

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Two proteins targeted to the same lytic granule compartment undergo very different posttranslational processing

21 January 2018

1 reference

Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

21 January 2018

1 reference

The molecular machinery for the biogenesis of lysosome-related organelles: lessons from Hermansky-Pudlak syndrome

21 January 2018

1 reference

Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6

21 January 2018

1 reference

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

21 January 2018

1 reference

Cappuccino, a mouse model of Hermansky-Pudlak syndrome, encodes a novel protein that is part of the pallidin-muted complex (BLOC-1)

21 January 2018

1 reference

Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)

21 January 2018

1 reference

Hermansky-Pudlak syndrome: vesicle formation from yeast to man.

21 January 2018

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Mutations in U6 snRNA that alter splice site specificity: implications for the active site.

21 January 2018

1 reference

Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome

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The mammalian AP-3 adaptor-like complex mediates the intracellular transport of lysosomal membrane glycoproteins.

21 January 2018

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The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform

21 January 2018

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Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing

21 January 2018

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A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex

21 January 2018

1 reference

Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet

21 January 2018

1 reference

Beta3A-adaptin, a subunit of the adaptor-like complex AP-3

21 January 2018

1 reference

AP-3: an adaptor-like protein complex with ubiquitous expression

21 January 2018

1 reference

A novel cytotoxic T lymphocyte activation assay. Optimized conditions for antigen receptor triggered granule enzyme secretion

21 January 2018

1 reference

Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome Patients

21 January 2018

1 reference

Mouse models of Hermansky Pudlak syndrome: a review

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Hermansky-Pudlak syndrome type 4 (HPS-4): clinical and molecular characteristics

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI1000

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16 January 2018

PubMed ID

14566336

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16 January 2018