53BP1 and BRCA1 control pathway choice for stalled replication restart (Q47127900)

8 January 2018

title

53BP1 and BRCA1 control pathway choice for stalled replication restart (English)

1 reference

8 January 2018

author

Dongyi Xu

8

1 reference

8 January 2018

author name string

Yixi Xu

1

1 reference

8 January 2018

Shaokai Ning

2

1 reference

8 January 2018

Zheng Wei

3

1 reference

8 January 2018

Ran Xu

4

1 reference

8 January 2018

Xinlin Xu

5

1 reference

8 January 2018

Mengtan Xing

6

1 reference

8 January 2018

Rong Guo

7

1 reference

8 January 2018

language of work or name

English

0 references

publication date

6 November 2017

1 reference

8 January 2018

published in

eLife

1 reference

8 January 2018

volume

6

1 reference

8 January 2018

BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination.

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Ewing Tumor-associated Antigen 1 Interacts with Replication Protein A to Promote Restart of Stalled Replication Forks

23 May 2018

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Replication fork stability confers chemoresistance in BRCA-deficient cells

23 May 2018

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Replication stress activates DNA repair synthesis in mitosis.

23 May 2018

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Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase

23 May 2018

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DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.

23 May 2018

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Preventing replication fork collapse to maintain genome integrity

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REV7 counteracts DNA double-strand break resection and affects PARP inhibition

23 May 2018

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MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

23 May 2018

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Replication fork reversal in eukaryotes: from dead end to dynamic response

23 May 2018

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Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

23 May 2018

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PTIP associates with Artemis to dictate DNA repair pathway choice

23 May 2018

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BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork

23 May 2018

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DNA replication and oncogene-induced replicative stress

23 May 2018

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MUS81-EME2 promotes replication fork restart

23 May 2018

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Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks

23 May 2018

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Mitosis inhibits DNA double-strand break repair to guard against telomere fusions

23 May 2018

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Double-strand break repair: 53BP1 comes into focus

23 May 2018

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Break-induced replication repair of damaged forks induces genomic duplications in human cells.

23 May 2018

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ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

23 May 2018

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RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells

23 May 2018

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Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells

23 May 2018

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Break-induced DNA replication

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

ATR phosphorylates SMARCAL1 to prevent replication fork collapse

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Break-induced replication: functions and molecular mechanism

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

RIF1 counteracts BRCA1-mediated end resection during DNA repair

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

23 May 2018

1 reference

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Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

53BP1 regulates DSB repair using Rif1 to control 5' end resection

23 May 2018

1 reference

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Multiplex genome engineering using CRISPR/Cas systems

23 May 2018

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A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

23 May 2018

1 reference

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BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair

23 May 2018

1 reference

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Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis

23 May 2018

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Differences in sensitivity to DNA-damaging Agents between XRCC4- and Artemis-deficient human cells

23 May 2018

1 reference

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Pathways of mammalian replication fork restart.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

PTIP promotes DNA double-strand break repair through homologous recombination

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

BRCA1 and its toolbox for the maintenance of genome integrity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Genetic dissection of vertebrate 53BP1: a major role in non-homologous end joining of DNA double strand breaks

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Polo-like kinases and the orchestration of cell division

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5683755

Role for BLM in replication-fork restart and suppression of origin firing after replicative stress

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29106372

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.7554/ELIFE.30523

1 reference

8 January 2018

PMCID

5683755

1 reference

8 January 2018

PubMed ID

29106372

1 reference

8 January 2018