Methylene blue rescues heart defects in a Drosophila model of Friedreich's ataxia. (Q47072694)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105471%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Methylene blue rescues heart defects in a Drosophila model of Friedreich's ataxia (English)

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27 February 2020

0 references

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GOA release 2020-03-11

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4

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27 February 2020

Herve Tricoire

1

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27 February 2020

author name string

Amandine Palandri

2

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27 February 2020

Arthur Bourdais

3

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27 February 2020

Véronique Monnier

5

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27 February 2020

publication date

8 October 2013

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27 February 2020

published in

Human Molecular Genetics

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27 February 2020

volume

23

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27 February 2020

issue

4

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27 February 2020

page(s)

968-979

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Clinical and genetic abnormalities in patients with Friedreich's ataxia

27 February 2020

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Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass

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Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia

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Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice

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Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia

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PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia

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Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxia

21 January 2018

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PPAR-gamma agonist Azelaoyl PAF increases frataxin protein and mRNA expression: new implications for the Friedreich's ataxia therapy.

21 January 2018

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Altered lipid metabolism in a Drosophila model of Friedreich's ataxia.

21 January 2018

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Flavin adenine dinucleotide rescues the phenotype of frataxin deficiency

21 January 2018

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Drosophila frataxin: an iron chaperone during cellular Fe-S cluster bioassembly

21 January 2018

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Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia

21 January 2018

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21 January 2018

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"Lest we forget you--methylene blue...".

21 January 2018

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dJun and Vri/dNFIL3 are major regulators of cardiac aging in Drosophila

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation

21 January 2018

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Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways

21 January 2018

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Methylene blue improves brain oxidative metabolism and memory retention in rats.

21 January 2018

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Antidote use in the critically ill poisoned patient

21 January 2018

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HEREDITARY DIAPHORASE DEFICIENCY AND METHEMOGLOBINEMIA

21 January 2018

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Concise review: methemoglobinemia

21 January 2018

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Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature

21 January 2018

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TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans

21 January 2018

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Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.

21 January 2018

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Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity

21 January 2018

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Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo.

21 January 2018

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Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish

21 January 2018

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Methylene blue prevents methylmalonate-induced seizures and oxidative damage in rat striatum.

21 January 2018

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Methylene blue prevents neurodegeneration caused by rotenone in the retina.

21 January 2018

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The steroid hormone receptor EcR finely modulates Drosophila lifespan during adulthood in a sex-specific manner.

21 January 2018

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Mitochondrial electron transport chain dysfunction during development does not extend lifespan in Drosophila melanogaster.

21 January 2018

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21 January 2018

Frataxin knockin mouse

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Antioxidant, EUK-8, Prevents Murine Dilated Cardiomyopathy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDT493

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105471%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105471%20AND%20SRC:MED&resulttype=core&format=json