Statin treatment increases formation of carbon monoxide and bilirubin in mice: a novel mechanism of in vivo antioxidant protection. (Q46976972)

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title

Statin treatment increases formation of carbon monoxide and bilirubin in mice: a novel mechanism of in vivo antioxidant protection (English)

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5

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Lucie Muchová

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Jaroslav Zelenka

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Ichiro Morioka

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author name string

Ronald J Wong

2

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Mark Hsu

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Henning Schröder

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David K Stevenson

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publication date

1 August 2007

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Canadian Journal of Physiology and Pharmacology

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published in

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volume

85

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page(s)

800-810

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issue

8

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Heme oxygenase and the cardiovascular-renal system

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cites work

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Heme oxygenase-1: a therapeutic amplification funnel

21 January 2018

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Biliverdin reductase: a major physiologic cytoprotectant

21 January 2018

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Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients

21 January 2018

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HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways.

21 January 2018

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Heme oxygenase-1 protects against vascular constriction and proliferation

21 January 2018

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Atorvastatin affects several angiogenic mediators in human endothelial cells

21 January 2018

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Heme oxygenase-1 induction may explain the antioxidant profile of aspirin

21 January 2018

1 reference

Rosuvastatin upregulates the antioxidant defense protein heme oxygenase-1.

21 January 2018

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The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells

21 January 2018

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Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease.

21 January 2018

1 reference

Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo.

21 January 2018

1 reference

Gene regulation of heme oxygenase-1 as a therapeutic target

21 January 2018

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Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection.

21 January 2018

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Atorvastatin prevents hypoxia-induced inhibition of endothelial nitric oxide synthase expression but does not affect heme oxygenase-1 in human microvascular endothelial cells

21 January 2018

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Heme oxygenase and cyclooxygenase in the central nervous system: a functional interplay.

21 January 2018

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Current perspectives on statins

21 January 2018

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Inhibition of the mevalonate pathway: benefits beyond cholesterol reduction?

21 January 2018

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Inhibition of LOX-1 by statins may relate to upregulation of eNOS.

21 January 2018

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Simvastatin ameliorates injury in an experimental model of lung ischemia-reperfusion

21 January 2018

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Pharmacokinetics and disposition of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in rat.

21 January 2018

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Heme oxygenase-1: unleashing the protective properties of heme

21 January 2018

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Atrial natriuretic peptide reduces cyclosporin toxicity in renal cells: role of cGMP and heme oxygenase-1.

21 January 2018

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Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance

21 January 2018

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Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

21 January 2018

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The evolving role of statins in the management of atherosclerosis

21 January 2018

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Cytoprotective and Antiproliferative Effects of HMG-CoA Reductase Inhibitors

21 January 2018

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Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels

21 January 2018

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Heme oxygenase activity as measured by carbon monoxide production

21 January 2018

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Determination of carbon monoxide (CO) in rodent tissue: effect of heme administration and environmental CO exposure

21 January 2018

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Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation

21 January 2018

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The lipid and non-lipid effects of statins

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y07-077

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