Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc. (Q46939297)

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9 January 2020

title

Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc (English)

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9 January 2020

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4

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9 January 2020

author name string

Rubén Alvarez-Rodríguez

series ordinal

1

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9 January 2020

Mercedes Barzi

series ordinal

2

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9 January 2020

Jordi Berenguer

series ordinal

3

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9 January 2020

language of work or name

English

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publication date

19 October 2007

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Journal of Biological Chemistry

9 January 2020

published in

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9 January 2020

volume

282

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9 January 2020

issue

51

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9 January 2020

page(s)

37170-37180

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Mechanisms of neural patterning and specification in the developing cerebellum

9 January 2020

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Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

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Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

21 January 2018

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Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

21 January 2018

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N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization

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A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis.

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Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma

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Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

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cAMP, an activator of protein kinase A, suppresses the expression of sonic hedgehog

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Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling.

21 January 2018

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Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells

21 January 2018

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Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

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c-myc is a downstream target of the Smad pathway

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Overexpression of a nuclear protein, TIEG, mimics transforming growth factor-beta action in human osteoblast cells

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Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells

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Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

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Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum

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The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types

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Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

21 January 2018

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Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth

21 January 2018

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The zinc finger transcription factor transforming growth factor beta-inducible early gene-1 confers myeloid-specific activation of the leukocyte integrin CD11d promoter

21 January 2018

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The TGF? inducible early gene plays a central role in the anti-proliferative response to TGF?

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Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor

21 January 2018

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21 January 2018

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E2F proteins regulate MYCN expression in neuroblastomas

21 January 2018

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N-myc oncogene expression in neuroblastoma is driven by Sp1 and Sp3

21 January 2018

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E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas.

21 January 2018

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The family feud: turning off Sp1 by Sp1-like KLF proteins

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M705414200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17951258%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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