Occupancy of a single anesthetic binding pocket is sufficient to enhance glycine receptor function. (Q46856382)

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10 January 2020

title

Occupancy of a single anesthetic binding pocket is sufficient to enhance glycine receptor function (English)

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10 January 2020

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1

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10 January 2020

author name string

Rachel Phelan

2

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10 January 2020

Beth S Erlichman

3

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10 January 2020

Rathi N Pillai

4

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10 January 2020

Lan Ma

5

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10 January 2020

Gregory F Lopreato

6

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10 January 2020

S John Mihic

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language of work or name

English

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publication date

16 December 2005

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Journal of Biological Chemistry

10 January 2020

published in

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10 January 2020

volume

281

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issue

6

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10 January 2020

page(s)

3305-3311

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Acute effects of ethanol on GABAA and glycine receptor function

10 January 2020

cites work

1 reference

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Molecular and neuronal substrates for general anaesthetics

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The glycinergic inhibitory synapse.

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Glycine receptors mediate part of the immobility produced by inhaled anesthetics

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Transgenic expression of a mutant glycine receptor decreases alcohol sensitivity of mice

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Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics

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Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes

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Antagonism of inhalant and volatile anesthetic enhancement of glycine receptor function

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Post-synaptic inhibitory mechanisms of anaesthesia; glycine receptors.

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Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer

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Molecular structure and function of the glycine receptor chloride channel

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Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

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Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

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Structure and gating mechanism of the acetylcholine receptor pore

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Minimum alveolar anesthetic concentration of fluorinated alkanols in rats: relevance to theories of narcosis

21 January 2018

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Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267.

21 January 2018

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Statistical coassembly of glycine receptor alpha1 wildtype and the hyperekplexia mutant alpha1(P250T) in HEK 293 cells: impaired channel function is not dominant in the recombinant system

21 January 2018

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GABA(A) receptors as molecular sites of ethanol action. Direct or indirect actions?

21 January 2018

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Enhancement of glycine receptor function by ethanol: role of phosphorylation

21 January 2018

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Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics

21 January 2018

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Molecular determinants of glycine receptor subunit assembly

21 January 2018

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Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures

21 January 2018

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Structural basis for the inhibition of firefly luciferase by a general anesthetic

21 January 2018

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Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster

21 January 2018

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Coupling of agonist binding to channel gating in the GABA(A) receptor

21 January 2018

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The activation mechanism of alpha1 homomeric glycine receptors

21 January 2018

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Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M502000200

1 reference

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10 January 2020

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