Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension (Q46853702)

25 December 2017

title

Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension (English)

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25 December 2017

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Hailan Zhou

1

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25 December 2017

Hanzhong Liu

2

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25 December 2017

Stacy L Porvasnik

3

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25 December 2017

Naohiro Terada

4

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25 December 2017

Anupam Agarwal

5

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25 December 2017

Yanping Cheng

6

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25 December 2017

Gary A Visner

7

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25 December 2017

publication date

1 January 2006

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25 December 2017

published in

Laboratory Investigation

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25 December 2017

volume

86

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25 December 2017

page(s)

62-71

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25 December 2017

issue

1

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.3700361

exact match

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cites work

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U-61, 431F, a stable prostacyclin analogue, inhibits the proliferation of bovine vascular smooth muscle cells with little antiproliferative effect on endothelial cells

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Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells

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7 January 2021

p70 S6 kinase-mediated protein synthesis is a critical step for vascular endothelial cell proliferation

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7 January 2021

Neointimal formation after balloon-induced vascular injury in Yucatan minipigs is reduced by oral rapamycin

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7 January 2021

Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model

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7 January 2021

Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions

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7 January 2021

40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats

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7 January 2021

The effect of immunosuppressants and adoptive transfer in monocrotaline pyrrole pneumotoxicity

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7 January 2021

Myofibroblast proliferation, fibrosis, and defective pancreatic repair induced by cyclosporin in rats

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7 January 2021

Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle

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7 January 2021

Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin

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7 January 2021

Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications

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7 January 2021

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

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7 January 2021

Adenovirus-mediated heme oxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Computerized morphometry of the pulmonary vasculature over a range of intravascular pressures.

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7 January 2021

Reduced stress defense in heme oxygenase 1-deficient cells.

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7 January 2021

Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse

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7 January 2021

A cis-acting region regulates oxidized lipid-mediated induction of the human heme oxygenase-1 gene in endothelial cells

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7 January 2021

Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathway

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7 January 2021

Transient enhancement of heme oxygenase 1 mRNA accumulation: a marker of oxidative stress to eukaryotic cells.

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Prevention of hypoxia-induced pulmonary hypertension by enhancement of endogenous heme oxygenase-1 in the rat

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Rapamycin attenuates load-induced cardiac hypertrophy in mice

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7 January 2021

Smad7-dependent regulation of heme oxygenase-1 by transforming growth factor-beta in human renal epithelial cells

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Human heme oxygenase: cell cycle-dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells.

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Bilirubin: a natural inhibitor of vascular smooth muscle cell proliferation

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

Heme protein-induced chronic renal inflammation: suppressive effect of induced heme oxygenase-1

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700361

7 January 2021

10.1038/LABINVEST.3700361

Identifiers

DOI

1 reference

25 December 2017

PubMed ID

16357868

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25 December 2017