Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers. (Q46791717)

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scientific article published on 3 November 2005

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English	Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers.	scientific article published on 3 November 2005

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8 January 2020

Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers (English)

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8 January 2020

phase II clinical trial

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Diane C. Bodurka

3

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8 January 2020

Charles F. Levenback

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Charles F Levenback

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8 January 2020

David Gershenson

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David M Gershenson

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Robert L Coleman

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8 January 2020

Russell R Broaddus

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8 January 2020

Judith K Wolf

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Thomas W Burke

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John J Kavanagh

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3 November 2005

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8 January 2020

Gynecologic Oncology

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101

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8 January 2020

126-131

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8 January 2020

1

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8 January 2020

Cancer statistics, 2005

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Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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Treatment of gastrointestinal stromal tumors with imatinib mesylate: a major breakthrough in the understanding of tumor-specific molecular characteristics

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Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma

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Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.

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Imatinib mesylate (Gleevec) inhibits ovarian cancer cell growth through a mechanism dependent on platelet-derived growth factor receptor alpha and Akt inactivation

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Expression of c-ABL, c-KIT, and platelet-derived growth factor receptor-beta in ovarian serous carcinoma and normal ovarian surface epithelium

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The effects of platelet-derived growth factor and receptor on normal and neoplastic human ovarian surface epithelium

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Abl expression in human fetal and adult tissues, tumours, and tumour microvessels

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Expression and action of kit ligand/stem cell factor in normal human and bovine ovarian surface epithelium and ovarian cancer

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Lack of expression of c-KIT in ovarian cancers is associated with poor prognosis

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Human ovarian tumors of epithelial origin express PDGF in vitro and in vivo

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Optimal two-stage designs for phase II clinical trials

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A phase II trial of imatinib mesylate in patients with prostate specific antigen progression after local therapy for prostate cancer

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Imatinib mesylate in patients with adenoid cystic cancers of the salivary glands expressing c-kit: a Princess Margaret Hospital phase II consortium study

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

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Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume.

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Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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Identifiers

10.1016/J.YGYNO.2005.09.041

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16271384%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16271384%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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