MEK-ERK signaling is involved in interferon-gamma-induced death of oligodendroglial progenitor cells (Q46736419)

24 December 2017

title

MEK-ERK signaling is involved in interferon-gamma-induced death of oligodendroglial progenitor cells (English)

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24 December 2017

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Makoto Horiuchi

1

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24 December 2017

Aki Itoh

series ordinal

2

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24 December 2017

David Pleasure

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3

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24 December 2017

Takayuki Itoh

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4

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24 December 2017

language of work or name

English

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publication date

25 May 2006

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

281

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24 December 2017

issue

29

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24 December 2017

page(s)

20095-20106

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24 December 2017

Mechanisms of immune injury in multiple sclerosis

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Interferon-gamma inhibits cell cycle exit in differentiating oligodendrocyte progenitor cells

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Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes.

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LPS/IFN-gamma cytotoxicity in oligodendroglial cells: role of nitric oxide and protection by the anti-inflammatory cytokine IL-10.

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AMPA glutamate receptor-mediated calcium signaling is transiently enhanced during development of oligodendrocytes.

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Cytokine-induced cell death in human oligodendroglial cell lines: I. Synergistic effects of IFN-gamma and TNF-alpha on apoptosis

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Alternative activation of STAT1 and STAT3 in response to interferon-gamma

21 January 2018

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Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicity

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Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

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Developmental differences in HO-induced oligodendrocyte cell death: role of glutathione, mitogen-activated protein kinases and caspase 3.

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Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo

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Cytokine induction of inducible nitric oxide synthase in an oligodendrocyte cell line: role of p38 mitogen-activated protein kinase activation

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Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis

21 January 2018

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Mammalian MAP kinase signalling cascades

21 January 2018

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Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

21 January 2018

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Decreased growth inhibitory responses of squamous carcinoma cells to interferon-gamma involve failure to recruit cki proteins into cdk2 complexes

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Cyclin E-CDK2 is a regulator of p27Kip1.

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Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

21 January 2018

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IFNgamma inhibition of cell growth in glioblastomas correlates with increased levels of the cyclin dependent kinase inhibitor p21WAF1/CIP1.

21 January 2018

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IFN-gamma induces apoptosis in developing mast cells

21 January 2018

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Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression

21 January 2018

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Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development

21 January 2018

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Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes

21 January 2018

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Reversible inhibitory effects of interferon-gamma and tumour necrosis factor-alpha on oligodendroglial lineage cell proliferation and differentiation in vitro

21 January 2018

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The role of p27Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cells

21 January 2018

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Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated: up-regulation of p27(Kip1)

21 January 2018

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Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M603179200

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24 December 2017

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24 December 2017