Glucose-induced Akt1 activation mediates fibronectin synthesis in endothelial cells (Q46727455)

24 December 2017

title

Glucose-induced Akt1 activation mediates fibronectin synthesis in endothelial cells (English)

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24 December 2017

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2

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author name string

X Xin

series ordinal

1

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24 December 2017

S Chen

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3

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24 December 2017

S Chakrabarti

series ordinal

4

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publication date

29 September 2005

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24 December 2017

published in

Diabetologia

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volume

48

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issue

11

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page(s)

2428-2436

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https://scigraph.springernature.com/pub.10.1007/s00125-005-1939-4

exact match

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cites work

Differential activation of NF-kappa B and AP-1 in increased fibronectin synthesis in target organs of diabetic complications

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High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1.

21 January 2018

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Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner

21 January 2018

1 reference

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Magnetic relaxation switches capable of sensing molecular interactions

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New insights into the role of nuclear factor-kB in cell growth regulation

21 January 2018

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Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

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12 December 2020

GSK-3: tricks of the trade for a multi-tasking kinase

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Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP

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Akt is a downstream target of NF-kappa B.

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Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes

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Proliferative effect of high glucose is modulated by antisense oligonucleotides against fibronectin in rat endothelial cells

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Cell surface interactions with extracellular materials

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Biochemistry and molecular cell biology of diabetic complications

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Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry

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Endothelins in chronic diabetic complications.

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Akt is more than just a Bad kinase

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Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

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Mitogen-activated protein kinases as glucose transducers for diabetic complications

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Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelin-mediated fibronectin synthesis

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Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling

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Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis

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Fibronectin overexpression in retinal microvessels of patients with diabetes

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The cellular and molecular mechanisms of diabetic complications

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Characterization of three different elements in the 5'-flanking region of the fibronectin gene which mediate a transcriptional response to cAMP

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Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus

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Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells.

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Oncofetal fibronectin in diabetic retinopathy.

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Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats

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Parallels in invasion and angiogenesis provide pivotal points for therapeutic intervention

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PKB/AKT: functional insights from genetic models

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Abnormalities in protein kinase C and MAP kinase cascade in mesangial cells cultured under high glucose conditions

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12 December 2020

PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells

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12 December 2020

Targets of B-cell antigen receptor signaling: the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3 signaling pathway and the Rap1 GTPase

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12 December 2020

Mechanisms and consequences of activation of protein kinase B/Akt

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12 December 2020

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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12 December 2020

Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo.

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Ten years of protein kinase B signalling: a hard Akt to follow

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Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR.

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Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

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12 December 2020

10.1007/S00125-005-1939-4

Identifiers

DOI

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24 December 2017

PubMed ID

16193290

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24 December 2017