Wobble modification defect suppresses translational activity of tRNAs with MERRF and MELAS mutations (Q46667489)

24 December 2017

title

Wobble modification defect suppresses translational activity of tRNAs with MERRF and MELAS mutations (English)

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24 December 2017

author

Tsutomu Suzuki

2

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24 December 2017

author name string

Takehiro Yasukawa

1

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24 December 2017

Shigeo Ohta

3

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24 December 2017

Kimitsuna Watanabe

4

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24 December 2017

publication date

1 November 2002

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24 December 2017

published in

Mitochondrion

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24 December 2017

volume

2

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24 December 2017

issue

1-2

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24 December 2017

page(s)

129-141

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24 December 2017

Single atom modification (O-->S) of tRNA confers ribosome binding.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Decreased aminoacylation of mutant tRNAs in MELAS but not in MERRF patients

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Phy M: an RNase activity specific for U and A residues useful in RNA sequence analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Complex I deficiency is associated with 3243G:C mitochondrial DNA in osteosarcoma cell cybrids

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

A tRNA suppressor mutation in human mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Mitochondrial tRNALeu isoforms in lung carcinoma cybrid cells containing the np 3243 mtDNA mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA(Lys) and premature translation termination

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Structural changes in base-paired region 28 in 16 S rRNA close to the decoding region of the 30 S ribosomal subunit are correlated to changes in tRNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Pathophysiology of the MELAS 3243 transition mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies.

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Synthetic polynucleotides and the amino acid code. VII

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

The deafness-associated mitochondrial DNA mutation at position 7445, which affects tRNASer(UCN) precursor processing, has long-range effects on NADH dehydrogenase subunit ND6 gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Accumulation of mtDNA with a mutation at position 3271 in tRNA(Leu)(UUR) gene introduced from a MELAS patient to HeLa cells lacking mtDNA results in progressive inhibition of mitochondrial respiratory function

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR).

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Impairment of mitochondrial transcription termination by a point mutation associated with the MELAS subgroup of mitochondrial encephalomyopathies

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Translation of synonymous codons in family boxes by Mycoplasma capricolum tRNAs with unmodified uridine or adenosine at the first anticodon position

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

The diabetes-associated 3243 mutation in the mitochondrial tRNA(Leu(UUR)) gene causes severe mitochondrial dysfunction without a strong decrease in protein synthesis rate

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Mitochondrial leucine tRNA mutation in neurological diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Protein degradation in mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

A point mutation in the mitochondrial tRNA(Leu)(UUR) gene in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes).

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Fine mapping of mitochondrial RNAs derived from the mtDNA region containing a point mutation associated with MELAS.

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Analysis of modified nucleosides and nucleotide sequence of tRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

In vitro 3'-end endonucleolytic processing defect in a human mitochondrial tRNA(Ser(UCN)) precursor with the U7445C substitution, which causes non-syndromic deafness

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Atypical clinical presentations associated with the MELAS mutation at position 3243 of human mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Recognition of cognate transfer RNA by the 30S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Mitochondrial DNA mutations at nucleotide positions 3243 and 3271 in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes: a comparative study

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Mitochondrial DNA mutations and pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Compilation of tRNA sequences and sequences of tRNA genes

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Codon-reading specificity of an unmodified form of Escherichia coli tRNA1Ser in cell-free protein synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Higher-order structure of bovine mitochondrial tRNA(Phe) lacking the 'conserved' GG and T psi CG sequences as inferred by enzymatic and chemical probing.

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Mapping the position of translational elongation factor EF-G in the ribosome by directed hydroxyl radical probing

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Modified nucleoside dependent Watson-Crick and wobble codon binding by tRNALysUUU species

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Modification defect at anticodon wobble nucleotide of mitochondrial tRNAs(Leu)(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Defect in modification at the anticodon wobble nucleotide of mitochondrial tRNA(Lys) with the MERRF encephalomyopathy pathogenic mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

A pathogenic point mutation reduces stability of mitochondrial mutant tRNA(Ile)

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Wobble modification defect in tRNA disturbs codon-anticodon interaction in a mitochondrial disease

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

Crystal structure of the ribosome at 5.5 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS1567-7249%2802%2900033-8

7 January 2021

10.1016/S1567-7249(02)00033-8

Identifiers

DOI

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24 December 2017

PubMed ID

16120315

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24 December 2017