Synthetic LXR agonists increase LDL in CETP species (Q46604868)

23 December 2017

title

Synthetic LXR agonists increase LDL in CETP species (English)

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23 December 2017

14

Karpagam Aravindhan

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23 December 2017

Beat M Jucker

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object named as

Beat Jucker

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23 December 2017

Robert N Willette

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object named as

Robert N Willette

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23 December 2017

author name string

Pieter H E Groot

1

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23 December 2017

Nigel J Pearce

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23 December 2017

John W Yates

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23 December 2017

Claire Stocker

4

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23 December 2017

Charles Sauermelch

5

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Christopher P Doe

6

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23 December 2017

Alan Olzinski

8

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Tambra Peters

9

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23 December 2017

Denise d'Epagnier

10

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Kathleen O Morasco

11

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23 December 2017

John A Krawiec

12

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Christine L Webb

13

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Mark Burgert

16

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23 December 2017

Chun Ma

17

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Joseph P Marino

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Jon L Collins

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Colin H Macphee

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Scott K Thompson

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Michael Jaye

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23 December 2017

publication date

16 July 2005

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23 December 2017

Journal of Lipid Research

published in

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23 December 2017

volume

46

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23 December 2017

issue

10

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23 December 2017

page(s)

2182-2191

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23 December 2017

LXR, a nuclear receptor that defines a distinct retinoid response pathway

cites work

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

The liver X receptor gene team: potential new players in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a).

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Role of LXRs in control of lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Orphan nuclear receptors find a home in the arterial wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

LXRs: new therapeutic targets in atherosclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Liver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Putative metabolic effects of the liver X receptor (LXR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Transcriptional activation of the stearoyl-CoA desaturase 2 gene by sterol regulatory element-binding protein/adipocyte determination and differentiation factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Crystal structure of the human liver X receptor beta ligand-binding domain in complex with a synthetic agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Crystal structure of the heterodimeric complex of LXR and RXR ligand-binding domains in a fully agonistic conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Connections and regulation of the human estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Raising HDL cholesterol without inducing hepatic steatosis and hypertriglyceridemia by a selective LXR modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500116-JLR200

10.1194/JLR.M500116-JLR200

21 January 2018

Identifiers

DOI

1 reference

23 December 2017

PubMed ID

16024916

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23 December 2017